New hope for hard-to-heal leg ulcers: cell therapy enters final testing

NCT ID NCT06489028

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 26 times

Summary

This phase 3 trial tests a topical cell therapy called Allo-APZ2-CVU for chronic venous leg ulcers that haven't healed with standard care. About 250 adults with ulcers between 1 and 25 cm² are enrolled. The goal is to see if the treatment leads to complete wound closure lasting at least two weeks, compared to a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • RHEACELL Clinical Trial Site

    Hialeah, Florida, 33012, United States

  • RHEACELL Clinical Trial Site

    Miami, Florida, 33136, United States

  • RHEACELL Clinical Trial Site

    Boston, Massachusetts, 02114, United States

  • RHEACELL Clinical Trial Site

    Minneapolis, Minnesota, 55455, United States

  • RHEACELL Clinical Trial Site

    Multiple Locations, Austria

  • RHEACELL Clinical Trial Site

    Multiple Locations, Czechia

  • RHEACELL Clinical Trial Site

    Multiple Locations, France

  • RHEACELL Clinical Trial Site

    Several Locations, Germany

  • RHEACELL Clinical Trial Site

    Multiple Locations, Hungary

  • RHEACELL Clinical Trial Site

    Multiple Locations, Italy

  • RHEACELL Clinical Trial Site

    Multiple Locations, Netherlands

  • RHEACELL Clinical Trial Site

    Multiple Locations, Poland

  • RHEACELL Clinical Trial Site

    Multiple Locations, Slovakia

  • RHEACELL Clinical Trial Site

    Multiple Locations, Sweden

  • RHEACELL Clinical Trial Site

    Multiple Locations, United Kingdom

Conditions

Explore the condition pages connected to this study.