VENOUS LEG ULCER

This study tests a special wound dressing called Hyalomatrix, made from hyaluronic acid, to see if it helps heal chronic venous leg ulcers faster than standard care alone. About 122 adults with leg ulcers that haven't healed for at least 4 weeks will take part. The main goal is t…

This Phase 2 study tests whether weekly injections of MTX-001, a substance made from human amniotic fluid, can help heal venous stasis ulcers that haven't improved after at least 4 weeks of standard care. About 80 adults aged 18 to 90 with non-infected leg ulcers will receive eit…

This study tests a device that uses light and magnets (COMS) to help heal chronic leg ulcers. About 122 people with venous leg ulcers will receive either standard care plus COMS or standard care alone. The goal is to see if the device speeds up wound healing and improves quality …

This study is testing a new skin graft made from donated amniotic tissue to help heal venous leg ulcers, which are slow-healing wounds caused by poor blood flow. Ten adults with a leg ulcer between 1 and 30 square centimeters will receive the graft and be monitored for up to 13 w…

This study tests a new hydrogel made with plasma-activated water on chronic wounds like diabetic foot ulcers and pressure sores. Fifty adults will either get the gel or standard wound care for 12 weeks. Researchers will check if the gel helps wounds close faster and lowers bacter…

This study tests a new medical device called the GORE VIAFORT stent, which is a small mesh tube placed inside a blocked or narrowed vein in the leg or pelvis to keep it open. The goal is to improve blood flow and reduce symptoms like pain, swelling, and leg ulcers. About 165 adul…

This study compares two types of skin grafts (PelloGraft and SanoGraft) to standard wound care for healing diabetic foot ulcers and venous leg ulcers. About 180 adults with chronic wounds will be enrolled. The goal is to see if these grafts help wounds close completely within 12 …

This study compares two versions of a special wound dressing for infected leg ulcers. One has an extra protective film on top. About 150 adults with infected leg ulcers will be randomly assigned to one dressing or the other, along with compression therapy. The main goal is to see…

This study tests a gel called ZKARE® for treating chronic ulcers that won't heal on their own. About 134 people with pressure sores, diabetic foot ulcers, or leg ulcers will either get the gel plus standard care, or standard care alone. The goal is to see if the gel helps wounds …

This Phase 3 trial tests whether a gel called TR987, applied to the skin, can help heal chronic leg ulcers caused by poor blood flow. About 312 adults with venous leg ulcers will receive either the gel plus standard wound care or standard care alone. The main goal is to see if th…

This study tests whether special wraps made from human placental membrane can help heal diabetic foot ulcers and venous leg ulcers that won't close on their own. About 50 adults with diabetes or venous disease will receive weekly applications of one of four placental membrane pro…

This study tests whether a special placental membrane called BR-AC, applied weekly, can help heal non-healing venous leg ulcers faster than standard care alone. About 60 adults with a leg ulcer between the knee and ankle will be randomly assigned to get either standard care plus …

This study tests whether a special tri-layer amnion graft or a single-layer amnion graft can help heal diabetic foot ulcers and venous leg ulcers that have not improved with standard care. About 165 adults with wounds between 2 and 25 cm² that have been open for over 4 weeks will…

This study is testing a pad used to clean wounds, such as diabetic ulcers, leg ulcers, pressure sores, surgical wounds, and burns. The goal is to see if the pad safely removes debris and improves the wound bed right after use. About 184 adults with these types of wounds will take…