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New gel could speed healing of stubborn leg wounds

NCT ID NCT06707090

Recruiting now Disease control Sponsor: TR Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether a gel called TR987, applied to the skin, can help heal chronic leg ulcers caused by poor blood flow. About 312 adults with venous leg ulcers will receive either the gel plus standard wound care or standard care alone. The main goal is to see if the gel leads to complete wound closure within 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
TR987 0.1% gel
What this could lead to
If successful, this gel could become a new treatment option to help heal stubborn leg ulcers faster and reduce pain.
What could go wrong
This is a Phase 3 trial, so results are not yet proven. The gel may not work better than standard care alone, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic ulcer of skin chronic venous insufficiency injury ulcer of lower limbs Varicose Ulcer venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-HEALING WOUND VENOUS INSUFFICIENCY OF LEG VENOUS LEG ULCER VENOUS STASIS VENOUS STASIS ULCER VENOUS ULCER WOUND HEAL WOUNDS

Contacts and locations

Locations

  • Clincial Research Site 01

    RECRUITING

    Lafayette, Louisiana, 70507, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 02

    RECRUITING

    McComb, Mississippi, 39648, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 04

    RECRUITING

    Bossier City, Louisiana, 71111, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 07

    RECRUITING

    D'Iberville, Mississippi, 39540, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 10

    RECRUITING

    O'Fallon, Illinois, 62269, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 11

    RECRUITING

    Los Angeles, California, 90063, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 13

    RECRUITING

    Pembrook Pines, Florida, 33026, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 14

    RECRUITING

    Fresno, California, 93710, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 18

    RECRUITING

    Suffolk, Virginia, 23434, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 19

    RECRUITING

    Miami, Florida, 33150, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 21

    ACTIVE_NOT_RECRUITING

    Tucson, Arizona, 85715, United States

  • Clincial Research Site 22

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

  • Clincial Research Site 23

    WITHDRAWN

    Mentor, Ohio, 44060, United States

  • Clincial Research Site 24

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 26

    RECRUITING

    Miami, Florida, 33156, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 28

    RECRUITING

    Tulsa, Oklahoma, 74137, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 30

    RECRUITING

    New York, New York, 10019, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 32

    RECRUITING

    Houston, Texas, 27707, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 34

    RECRUITING

    Chicago, Illinois, 60649, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 36

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 37

    RECRUITING

    Syosset, New York, 11791, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 38

    NOT_YET_RECRUITING

    Hollywood, Florida, 33021, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 40

    RECRUITING

    Jacksonville, Florida, 32209, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 43A

    RECRUITING

    San Francisco, California, 94115, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 43B

    RECRUITING

    San Francisco, California, 94117, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 43C

    RECRUITING

    Castro Valley, California, 94546, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 45

    WITHDRAWN

    Grove City, Ohio, 43123, United States

  • Clincial Research Site 46

    NOT_YET_RECRUITING

    San Antonio, Texas, 78224, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 47

    ACTIVE_NOT_RECRUITING

    Deerfield Beach, Florida, 33442, United States

  • Clincial Research Site 49

    RECRUITING

    Springfield, Illinois, 62704, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 51

    WITHDRAWN

    Tamarac, Florida, 33321, United States

  • Clincial Research Site 54

    RECRUITING

    Vista, California, 92081, United States

    Contact Email: •••••@•••••

  • Clincial Research Site 55

    ACTIVE_NOT_RECRUITING

    Winston-Salem, North Carolina, 27157, United States

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