New gel could speed healing of stubborn leg wounds

NCT ID NCT06707090

Recruiting now Disease control Sponsor: TR Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether a gel called TR987, applied to the skin, can help heal chronic leg ulcers caused by poor blood flow. About 312 adults with venous leg ulcers will receive either the gel plus standard wound care or standard care alone. The main goal is to see if the gel leads to complete wound closure within 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TR987 0.1% gel

What this could lead to

If successful, this gel could become a new treatment option to help heal stubborn leg ulcers faster and reduce pain.

What could go wrong

This is a Phase 3 trial, so results are not yet proven. The gel may not work better than standard care alone, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic ulcer of skin chronic venous insufficiency injury ulcer of lower limbs Varicose Ulcer venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-HEALING WOUND VENOUS INSUFFICIENCY OF LEG VENOUS LEG ULCER VENOUS STASIS VENOUS STASIS ULCER VENOUS ULCER WOUND HEAL WOUNDS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Clincial Research Site 01
RECRUITING

Lafayette, Louisiana, 70507, United States

Contact Email: •••••@•••••
Clincial Research Site 02
RECRUITING

McComb, Mississippi, 39648, United States

Contact Email: •••••@•••••
Clincial Research Site 04
RECRUITING

Bossier City, Louisiana, 71111, United States

Contact Email: •••••@•••••
Clincial Research Site 07
RECRUITING

D'Iberville, Mississippi, 39540, United States

Contact Email: •••••@•••••
Clincial Research Site 10
RECRUITING

O'Fallon, Illinois, 62269, United States

Contact Email: •••••@•••••
Clincial Research Site 11
RECRUITING

Los Angeles, California, 90063, United States

Contact Email: •••••@•••••
Clincial Research Site 13
RECRUITING

Pembrook Pines, Florida, 33026, United States

Contact Email: •••••@•••••
Clincial Research Site 14
RECRUITING

Fresno, California, 93710, United States

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Clincial Research Site 18
RECRUITING

Suffolk, Virginia, 23434, United States

Contact Email: •••••@•••••
Clincial Research Site 19
RECRUITING

Miami, Florida, 33150, United States

Contact Email: •••••@•••••
Clincial Research Site 21
ACTIVE_NOT_RECRUITING

Tucson, Arizona, 85715, United States
Clincial Research Site 22
NOT_YET_RECRUITING

Chicago, Illinois, 60611, United States
Clincial Research Site 23
WITHDRAWN

Mentor, Ohio, 44060, United States
Clincial Research Site 24
RECRUITING

Fort Worth, Texas, 76104, United States

Contact Email: •••••@•••••
Clincial Research Site 26
RECRUITING

Miami, Florida, 33156, United States

Contact Email: •••••@•••••
Clincial Research Site 28
RECRUITING

Tulsa, Oklahoma, 74137, United States

Contact Email: •••••@•••••
Clincial Research Site 30
RECRUITING

New York, New York, 10019, United States

Contact Email: •••••@•••••
Clincial Research Site 32
RECRUITING

Houston, Texas, 27707, United States

Contact Email: •••••@•••••
Clincial Research Site 34
RECRUITING

Chicago, Illinois, 60649, United States

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Clincial Research Site 36
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

Contact Email: •••••@•••••
Clincial Research Site 37
RECRUITING

Syosset, New York, 11791, United States

Contact Email: •••••@•••••
Clincial Research Site 38
NOT_YET_RECRUITING

Hollywood, Florida, 33021, United States

Contact Email: •••••@•••••
Clincial Research Site 40
RECRUITING

Jacksonville, Florida, 32209, United States

Contact Email: •••••@•••••
Clincial Research Site 43A
RECRUITING

San Francisco, California, 94115, United States

Contact Email: •••••@•••••
Clincial Research Site 43B
RECRUITING

San Francisco, California, 94117, United States

Contact Email: •••••@•••••
Clincial Research Site 43C
RECRUITING

Castro Valley, California, 94546, United States

Contact Email: •••••@•••••
Clincial Research Site 45
WITHDRAWN

Grove City, Ohio, 43123, United States
Clincial Research Site 46
NOT_YET_RECRUITING

San Antonio, Texas, 78224, United States

Contact Email: •••••@•••••
Clincial Research Site 47
ACTIVE_NOT_RECRUITING

Deerfield Beach, Florida, 33442, United States
Clincial Research Site 49
RECRUITING

Springfield, Illinois, 62704, United States

Contact Email: •••••@•••••
Clincial Research Site 51
WITHDRAWN

Tamarac, Florida, 33321, United States
Clincial Research Site 54
RECRUITING

Vista, California, 92081, United States

Contact Email: •••••@•••••
Clincial Research Site 55
ACTIVE_NOT_RECRUITING

Winston-Salem, North Carolina, 27157, United States