Assistance Publique - Hôpitaux De Paris

This study was designed to test a combination of two experimental drugs, monalizumab and MEDI5752, in people with MSI or dMMR metastatic cancers (cancers that have spread). These cancers often respond to immunotherapy, and the goal was to see if the combination could work better.…

This study tests whether giving two immunotherapy drugs (durvalumab and tremelimumab) before and after a standard liver cancer ablation procedure can help keep the cancer from coming back. About 30 adults with early-stage liver cancer will receive one infusion of the drug combina…

This study aimed to see if adding hydroxychloroquine to standard treatment (aspirin and blood thinners) could help more women with antiphospholipid syndrome have a healthy full-term pregnancy. The trial was withdrawn before any participants were enrolled, so no results are availa…

This study planned to test the drug eculizumab in kidney transplant patients who had signs of rejection not yet causing symptoms. The goal was to see if blocking part of the immune system could prevent long-term kidney damage. However, the trial was withdrawn before enrolling any…

This study was designed to see if an educational game called Yapouni could help children aged 3 to 16 and their parents feel more comfortable with CPAP or NIV machines used for sleep breathing problems. The study planned to compare standard teaching versus teaching plus the game,…

This study aimed to look back at the safety and effectiveness of hydroxychloroquine in children with Lipin-1 deficiency, a rare genetic condition causing severe muscle breakdown and pain. Researchers planned to review medical records of patients who had already received the drug …

This study was designed to see if MRI can measure blood flow in the placenta during pregnancy, especially in cases where the baby is not growing well (called IUGR). The researchers planned to compare MRI scans from pregnant women with and without growth problems. However, the stu…

This study planned to use heart MRI scans and blood tests to track heart muscle changes in people with Duchenne muscular dystrophy. It aimed to include participants aged 6 and older with a confirmed genetic diagnosis. However, the study was withdrawn before enrolling any particip…

This study looks at whether a new way of analyzing CT scans (called radiomics) can help doctors tell early on if chemotherapy is working for people with advanced pancreatic cancer. Researchers will study 400 adults with metastatic pancreatic cancer who are starting their first ro…

This study aimed to find out if a patient's body language and behavior during a pre-surgery talk with a nurse could reveal their anxiety level. Researchers planned to video record the conversation and compare behaviors to how anxious patients said they felt. The study was withdra…

This study looks at whether a fast, automatic eye test can predict delirium (sudden confusion) in intensive care patients who need a breathing machine. Delirium is common and serious in the ICU, but current detection methods are slow and require special training. Researchers will…

This study planned to follow nursing mothers who had a breast abscess treated with ultrasound-guided puncture. Researchers wanted to learn what factors help women continue breastfeeding and whether the treatment followed best practices. However, the study was withdrawn before enr…