Can a heart drug save lives in septic shock? new trial aims to find out.

NCT ID NCT04031573

First seen Apr 07, 2026 · Last updated Jun 09, 2026 · Updated 8 times

Summary

This study tests a drug called ivabradine in 429 adults with septic shock, a life-threatening condition where infection causes dangerously low blood pressure. Many patients develop a fast heart rate, which can worsen outcomes. Ivabradine slows the heart without weakening its pumping strength, unlike standard beta-blockers. The goal is to see if controlling heart rate this way reduces deaths at 28 days.

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Contacts and locations

Locations

  • Henri Mondor Hospital

    Créteil, 94000, France

Conditions

Explore the condition pages connected to this study.