Eye surgery trial to prevent blindness in stickler syndrome pulled before start

NCT ID NCT04465188

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to see if a surgical procedure called scleral buckling could prevent retinal detachment in people with Stickler syndrome, a genetic condition that raises the risk of vision loss. The plan was to treat one eye in patients aged 5 to 35 who had already lost vision in the other eye. However, the trial was withdrawn before enrolling any participants, so no conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
scleral buckle surgical procedure
What this could lead to
If it had worked, this could have pointed toward a way to prevent retinal detachment and vision loss in people with Stickler syndrome.
What could go wrong
The trial was withdrawn before it started, so no results are available. Even if it had run, it was a small early-phase study, and surgery carries risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Cochin

    Paris, 75014, France