Can a 48-hour drug delay preterm birth and save babies?

NCT ID NCT03976063

First seen Nov 20, 2025 · Last updated Apr 30, 2026 · Updated 17 times

Summary

This study tests whether giving a short course (48 hours) of tocolysis—medication that stops contractions—can reduce death or serious health problems in babies born after preterm premature rupture of membranes (PPROM) between 22 and 33 weeks of pregnancy. About 857 pregnant people with a single baby and no signs of infection are participating. The goal is to see if this brief treatment improves outcomes without requiring long-term medication.

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Contacts and locations

Locations

  • Trousseau University Hospital

    Paris, 75012, France

Conditions

Explore the condition pages connected to this study.