48-Hour drug may improve outcomes in preterm membrane rupture

NCT ID NCT03976063

First seen Nov 20, 2025 · Last updated Jun 11, 2026 · Updated 28 times

Summary

This study tests whether giving a short-term (48-hour) medication to stop contractions can improve survival and reduce severe health problems in babies when the water breaks early (between 22 and 34 weeks of pregnancy). About 857 pregnant people with a single baby and no signs of infection are participating. The goal is to see if this approach can safely delay delivery and lower the risk of complications like breathing difficulties or brain injury.

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Contacts and locations

Locations

  • Trousseau University Hospital

    Paris, 75012, France

Conditions

Explore the condition pages connected to this study.