New hope for rare disease: drug may slash steroid dependence

NCT ID NCT05030155

First seen Nov 20, 2025 · Last updated Jun 09, 2026 · Updated 24 times

Summary

This study tests if a drug called mepolizumab can help people with a rare disease called EGPA (which causes inflammation in blood vessels, asthma, and sinus problems) use less steroids while keeping the disease under control. About 100 adults with active EGPA will receive either mepolizumab or standard treatment. The main goal is to see if more people on mepolizumab can lower their daily steroid dose to 4 mg or less without having a relapse.

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Contacts and locations

Locations

  • Service de Médecine Interne, Centre de référence " Maladies systémiques et autoimmunes rares, en particulier Vascularites nécrosantes et Sclérodermies systémiques "Hôpital Cochin

    Paris, 75014, France

Conditions

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