ULCERATIVE COLITIS
Clinical trials for ULCERATIVE COLITIS explained in plain language.
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Real-world study confirms Entyvio's safety for ulcerative colitis patients
Disease control CompletedThis study looked at the long-term safety and effectiveness of the drug vedolizumab (Entyvio) in over 1,100 people with moderate to severe ulcerative colitis. Participants had not responded well to other treatments. The goal was to see how well the drug works and what side effect…
Matched conditions: ULCERATIVE COLITIS
Sponsor: Takeda • Aim: Disease control
Last updated Apr 28, 2026 20:20 UTC
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Blood tests may fine-tune biologic therapy for bowel disease
Disease control CompletedThis study looked at whether measuring the amount of anti-TNF medication and antibodies in the blood can help doctors make better treatment decisions for people with Crohn's disease or ulcerative colitis. About 260 patients were split into two groups: one where doctors used these…
Matched conditions: ULCERATIVE COLITIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated Apr 28, 2026 20:20 UTC
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Fasting diet shows promise for IBD-Related depression
Symptom relief CompletedThis study looked at whether a short-term, plant-based low-calorie diet (called a fasting mimicking diet) could improve depressive symptoms in people with inflammatory bowel disease (IBD). 42 adults with IBD and mild-to-moderate depression completed three 5-day diet cycles. Resea…
Matched conditions: ULCERATIVE COLITIS
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Apr 28, 2026 20:23 UTC
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New shot formula may hurt less: study tests patient comfort
Symptom relief CompletedThis study involved 324 adults with conditions like Crohn's disease, arthritis, or psoriasis who were already using a standard adalimumab injection. They switched to a higher-concentration version (AVT-02) to see if it caused less pain at the injection site and if patients stuck …
Matched conditions: ULCERATIVE COLITIS
Sponsor: Jamp Pharma Corporation • Aim: Symptom relief
Last updated Apr 28, 2026 20:21 UTC
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New study reveals infection risks of IBD drugs in seniors
Knowledge-focused CompletedThis study examined infection rates in nearly 24,000 older adults (65+) with ulcerative colitis or Crohn's disease who started treatment with ENTYVIO, TNF-alpha inhibitors, or ustekinumab. Using Medicare claims data from 2016 to 2025, researchers compared how many people had seri…
Matched conditions: ULCERATIVE COLITIS
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Apr 28, 2026 20:21 UTC
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Polish study watches IBD patients pick their vedolizumab shot – no treatment involved!
Knowledge-focused CompletedThis study watched 165 people with inflammatory bowel disease (Crohn's or colitis) in Poland as they started or continued vedolizumab treatment. Researchers did not give any treatment – they simply recorded whether patients chose intravenous (IV) or at-home injections, and tracke…
Matched conditions: ULCERATIVE COLITIS
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Apr 28, 2026 20:20 UTC