Could a bile acid pill ease ulcerative colitis?
NCT ID NCT04114292
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tested whether TUDCA, a bile acid supplement, is safe and can reduce stress in gut cells of people with active ulcerative colitis. Fourteen adults took TUDCA for 6 weeks while researchers measured changes in cell stress markers from colon biopsies. The goal was to see if TUDCA could help control the disease, not cure it.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Barnes-Jewish Hospital
St Louis, Missouri, 63110, United States
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Barnes-Jewish West County Hospital
Creve Coeur, Missouri, 63141, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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