Mini-Guts grown from patient biopsies could reveal new treatments for IBD

NCT ID NCT05425901

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study took small tissue samples from 16 people with or without inflammatory bowel disease (IBD) during routine colonoscopies. Researchers grew these samples into mini-organs called organoids in the lab. They then tested how these organoids respond to radiation and potential treatments, aiming to create a tool for testing new therapies for IBD and radiation damage to the gut. The study did not offer any direct treatment to participants.

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Contacts and locations

Locations

  • Groupe Hospitalier Ambroise Paré Hartmann

    Neuilly-sur-Seine, Hauts-de-Seine, 92200, France

Conditions

Explore the condition pages connected to this study.