Mini organs from biopsies could revolutionize gut disease research
NCT ID NCT05425901
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study takes small tissue samples from people with inflammatory bowel disease (IBD) and healthy volunteers to grow 'mini guts' (organoids) in the lab. Researchers will then expose these organoids to radiation to mimic radiation enteritis and test potential treatments. The goal is to create a reliable screening tool for new therapies, not to treat participants directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could create a lab-grown model to screen drugs for IBD and radiation gut damage, speeding up discovery of new treatments.
What could go wrong
This is a very early, small study (16 people) focused on building a tool, not testing a treatment. The organoid model may not fully mimic human disease.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Groupe Hospitalier Ambroise Paré Hartmann
Neuilly-sur-Seine, Hauts-de-Seine, 92200, France