Could a common plant compound tame ulcerative colitis?

NCT ID NCT07370220

Completed Disease control Sponsor: Benha University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether rutin, a natural compound found in plants, can help people with ulcerative colitis. 60 adults took rutin tablets or a placebo for 30 days. The goal was to see if rutin reduces gut inflammation and improves symptoms like diarrhea and abdominal pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Rutin (a plant-derived flavonoid) taken as 500 mg oral tablets twice daily for 30 days
What this could lead to: If it works, this could point toward a new, natural treatment option for ulcerative colitis that reduces gut inflammation and improves symptoms.
What could go wrong: This is a small, early-phase trial (60 people) with short follow-up. Results may not apply to all patients, and the benefit over placebo may be modest or absent. Side effects or lack of long-term data are also unknowns.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ULCERATIVE COLITIS

Contacts and locations

Locations

Benha Faculty of Medicine

Banhā, Al Qalyoubia, 13511, Egypt

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