ULCERATIVE COLITIS

This study tested a new drug called efavaleukin alfa in 221 adults with moderate to severe ulcerative colitis. The goal was to see if it could help patients achieve remission after 12 weeks of treatment. The trial was terminated early, so final results are limited, but the data m…

This study tested whether statins, a common cholesterol drug, could change the gut bacteria in people with ulcerative colitis to a healthier type. The goal was to see if this bacterial change could help control the disease. The trial was stopped early and involved 177 adults with…

This study tested a drug called efavaleukin alfa in 25 adults with moderate to severe ulcerative colitis. The goal was to see if the drug is safe and helps control symptoms over 1 to 2 years. The study was stopped early, but results may still help understand long-term treatment o…

This study aimed to see if a new medicine called AVT16 works as well as the approved drug Entyvio for people with moderate to severe ulcerative colitis. It included 301 adults aged 18 to 80. The study was terminated early, so results are limited.

This study tested an oral medicine called PF-07054894 in 44 adults with mild to severe ulcerative colitis. The goal was to see if it could safely help control the disease by reducing inflammation and symptoms. The trial was terminated early, so results are limited.

This study aimed to see how well tofacitinib (Xeljanz) works for people with moderate to severe ulcerative colitis in everyday medical practice in Switzerland. Researchers planned to track symptoms and gut inflammation in 18 adults over 8 weeks. However, the study was stopped ear…

This study tested an experimental oral treatment called VE202 for people with mild-to-moderate ulcerative colitis, a chronic inflammatory bowel disease. The treatment uses live bacteria to help restore gut balance. The trial was terminated early, so results are limited. Participa…

This study tested a drug called vixarelimab in 79 people with moderate to severe ulcerative colitis (UC) who had not responded well to other treatments. The goal was to see if the drug could help control the disease and reduce symptoms like diarrhea and bleeding. The study was st…

This study tested a stem cell product called Remestemcel-L in 7 adults with severe ulcerative colitis that did not get better with standard treatments. The goal was to see if injecting these cells into the colon was safe and could help patients avoid surgery or stronger drugs. Th…

This study tested whether a bile acid supplement called UDCA could reduce inflammation and improve quality of life in people with pouchitis, a complication after colon removal surgery for ulcerative colitis. Only 2 participants were enrolled before the study was stopped early. Th…

This study looked at whether adding high-dose steroid pulses to the usual oral steroid course could help people with moderate ulcerative colitis flares achieve remission without needing other treatments. The trial was terminated early and enrolled 75 adults with left-sided or ext…