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Gut bacteria pill for colitis shows early promise, but trial stopped early

NCT ID NCT05370885

Terminated Disease control Sponsor: Vedanta Biosciences, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental oral treatment called VE202 for people with mild-to-moderate ulcerative colitis, a chronic inflammatory bowel disease. The treatment uses live bacteria to help restore gut balance. The trial was terminated early, so results are limited. Participants took VE202 or a placebo for 2 or 8 weeks, and researchers looked at safety and whether the treatment improved colon inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLITIS, ULCERATIVE ULCERATIVE COLITIS

Contacts and locations

Locations

  • Artes Medikum, Medial Center, Llc

    Kyiv, 02002, Ukraine

  • Atlanta Center for Gastroenterology, P.C. & Atlanta Endoscopy Center, LTD

    Decatur, Georgia, 30033-6146, United States

  • Barts Health NHS TrustThe Royal London Hospital

    London, E1 2AJ, United Kingdom

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Bonifraterskie Centrum Medyczne Sp. z o.o

    Lodz, Łódź Voivodeship, 93-357, Poland

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

  • Centrum Medyczne "MEDYK"

    Rzeszów, Podkarpackie Voivodeship, 35-326, Poland

  • Chernivtsi Regional Clinical Hospital

    Chernivtsi, 03110, Ukraine

  • Clinical Research Center Spółka z ograniczoną odpowiedzialnością Medic-R Spółka komandytowa

    Poznan, Greater Poland Voivodeship, 61-731, Poland

  • Concord Repatriation General Hospital

    Concord, New South Wales, 2139, Australia

  • Cornell University Weill Cornell Medicine New York Presbyterian Hospital

    New York, New York, 10021, United States

  • Dept. Gastroenterology, Univ. Debrecen

    Debrecen, H-4032, Hungary

  • Endoskopia Sp. z o.o.

    Sopot, Pomeranian Voivodeship, 81-756, Poland

  • GI Pros Research

    Naples, Florida, 34102, United States

  • Gastroenterology Research of America, LLC

    San Antonio, Texas, 78229, United States

  • Imperial College Healthcare NHS Trust - St Mary's Hospital

    London, W2 1NY, United Kingdom

  • King's College Hospital

    London, SE5 9RS, United Kingdom

  • LLC Medical Center "Consilium Medical"

    Kyiv, 04050, Ukraine

  • Leiden University Medical Center

    Leiden, 2333 ZA, Netherlands

  • M.Sklifosovsky Poltava Regional Clinical Hospital Regional Gastroenterology Center

    Poltava, Poltavska, 36011, Ukraine

  • MEDICAL NETWORK Sp. z o.o. WIP Warsaw IBD Point

    Warsaw, Masovian Voivodeship, 04-501, Poland

  • Mater Misericordiae Ltd and Mater Research Ltd

    South Brisbane, Queensland, 4101, Australia

  • Medical Center OK!Clinic+

    Kyiv, 02091, Ukraine

  • Medical Centre Asklepion Main

    Sofia, 1303, Bulgaria

  • Medrise Sp. z o.o.

    Lublin, Lublin Voivodeship, 20-582, Poland

  • Municipal Nonprofit enterprise Kyiv City Clinical Hospital # 18

    Kyiv, 01054, Ukraine

  • NYU IBD Center

    New York, New York, 10016, United States

  • National Institute of Surgery and Transplantology named after O. O. Shalimova

    Kyiv, 03126, Ukraine

  • Pannónia Magánorvosi Centrum Kft

    Budapest, 1136, Hungary

  • PreventaMed s.r.o, Vila zdraví

    Olomouc, 77900, Czechia

  • Radboud Universitair Medisch Centrum

    Nijmegen, Gelderland, 6525 GA, Netherlands

  • Regional Clinical Hospital of the Ivano-Frankivsk Regional Council

    Ivano-Frankivsk, 76000, Ukraine

  • Revival Clinical Research

    Orlando, Florida, 32807, United States

  • Semmelweis Egyetem Belgyógyászati és Hematológiai Klinika

    Budapest, 1088, Hungary

  • Solumed Centrum Medyczne

    Poznan, 60-529, Poland

  • St Vincent's Hospital Melbourne Department of Gastroenterology

    Fitzroy, Victoria, 3065, Australia

  • Ternopil Regional Clinical Hospital

    Ternopil, 46002, Ukraine

  • Transcarpathian Regional Clinical Hospital named after Andria Novak

    Uzhhorod, 88018, Ukraine

  • UHB NHSFT Queen Elizabeth Hospital

    Birmingham, West Midlands, B15 2TH, United Kingdom

  • UMHAT Medica Ruse OOD

    Rousse, 7013, Bulgaria

  • University of Utah Hospitals and Clinics

    Salt Lake City, Utah, 84132, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

  • Uzhgorod City Multidisciplinary Clinical Hospital

    Uzhhorod, 88009, Ukraine

  • Vilnius University Hospital Santaros klinikos

    Vilnius, LT-08661, Lithuania

  • Vinnytsia City Clinical Hospital No. 1

    Vinnytsia, 21029, Ukraine

  • Vinnytsia Regional Clinical Hospital named after M.I. Pirogov

    Vinnytsia, 21000, Ukraine

  • Vita Longa Sp. z o.o.

    Katowice, 40748, Poland

  • Vojenská nemocnice Brno, Interní oddělení

    Brno, 61500, Czechia

  • Volyn Regional Clinical hospital

    Lutsk, 43000, Ukraine

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