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Steroid combo fails to show benefit for UC flares

NCT ID NCT02921555

Terminated Symptom relief Sponsor: Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding high-dose steroid pulses to the usual oral steroid course could help people with moderate ulcerative colitis flares achieve remission without needing other treatments. The trial was terminated early and enrolled 75 adults with left-sided or extensive colitis. The main goal was to see if the combination led to steroid-free endoscopic remission.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ULCERATIVE COLITIS

Contacts and locations

Locations

  • Althaia, xarxa assistencial universitaria de Manresa

    Manresa, Barcelona, 08243, Spain

  • Complejo Hospitalario Universitario Santiago de Compostela

    Santiago de Compostela, A Coruña, Spain

  • Consorci Corporació Sanitària Parc Taulí

    Sabadell, Barcelona, 08208, Spain

  • Consorci Hospitalari de Terrassa

    Terrassa, Barcelona, 08227, Spain

  • Hospital 12 de Octubre

    Madrid, Spain

  • Hospital Clínico de Valencia

    Valencia, 46010, Spain

  • Hospital De La Princesa

    Madrid, 28006, Spain

  • Hospital General Universitario de Alicante

    Alicante, Spain

  • Hospital Germans Trias i Pujol

    Badalona, Barcelona, 08916, Spain

  • Hospital Gregorio Marañon

    Madrid, 28007, Spain

  • Hospital Moisès Broggi

    Sant Joan Despí, Barcelona, 08970, Spain

  • Hospital Universitari Dr. Josep Trueta

    Girona, 17007, Spain

  • Hospital Universitari La Fe

    Valencia, Spain

  • Hospital Universitario Central de Asturias

    Oviedo, Principality of Asturias, 33011, Spain

  • Hospital Universitario Cruces

    Barakaldo, Vizcaya, 48903, Spain

  • Hospital Universitario General de Valencia

    Valencia, 46010, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Marqués de Valdecilla

    Santander, Cantabria, 39008, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, Spain

  • Hospital Universitario Reina Sofia

    Córdoba, 14004, Spain

  • Hospital Universitario Río Hortega

    Valladolid, 47012, Spain

  • Hospital Universitario de Ourense

    Ourense, Ourense, 32005, Spain

  • Hospital de Galdakao

    Galdakao, Bilbao, Spain

  • Hospital de Manises

    Valencia, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Spain

  • Hospital del Mar

    Barcelona, Spain

  • Hospital Álvaro Cunqueiro

    Vigo, Pontevedra, 36312, Spain

  • Mútua de Terrassa

    Terrassa, 08227, Spain

  • hospital Puerta de Hierro-Majadahonda

    Majadahonda, Madrid, 28222, Spain

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