Gut bacteria boost: can probiotics help ulcerative colitis patients stay in remission?

NCT ID NCT07180186

Completed Disease control Sponsor: Tanta University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether adding probiotics (Bacillus Clausii) to standard mesalamine treatment helps people with ulcerative colitis stay in remission. 70 adults in remission were split into groups: mesalamine alone, probiotics alone, or both. Researchers tracked disease activity, body mass index, and gut bacteria over a year. The goal was to see if probiotics could improve gut health and prevent flare-ups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Probiotics (Bacillus Clausii) and mesalamine
What this could lead to: If probiotics help maintain remission, this could point toward a simple add-on treatment to reduce flare-ups in ulcerative colitis.
What could go wrong: This is a small, completed study in a specific population (Egyptian patients). Results may not apply to other groups, and probiotics are not a replacement for standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MICROBIOTA PROBIOTIC THERAPY ULCERATIVE COLITIS

Contacts and locations

Locations

Tanta University

Tanta, El-Gharbia, 31527, Egypt

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