Gut bacteria boost: can probiotics help ulcerative colitis patients stay in remission?
NCT ID NCT07180186
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether adding probiotics (Bacillus Clausii) to standard mesalamine treatment helps people with ulcerative colitis stay in remission. 70 adults in remission were split into groups: mesalamine alone, probiotics alone, or both. Researchers tracked disease activity, body mass index, and gut bacteria over a year. The goal was to see if probiotics could improve gut health and prevent flare-ups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Probiotics (Bacillus Clausii) and mesalamine
What this could lead to
If probiotics help maintain remission, this could point toward a simple add-on treatment to reduce flare-ups in ulcerative colitis.
What could go wrong
This is a small, completed study in a specific population (Egyptian patients). Results may not apply to other groups, and probiotics are not a replacement for standard care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Tanta University
Tanta, El-Gharbia, 31527, Egypt