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Blood test guides smarter IBD treatment in landmark trial

NCT ID NCT05180175

Completed Disease control Sponsor: Region Örebro County Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a blood test measuring proteins can help doctors choose the best treatment for people newly diagnosed with inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. 300 patients were split into two groups: one where doctors had the protein test results and used a more aggressive treatment plan for high-risk patients, and another where doctors used standard care. The goal was to see if the personalized approach led to better disease control and quality of life after one year.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE INFLAMMATORY BOWEL DISEASES ULCERATIVE COLITIS

Contacts and locations

Locations

  • Akademiska Sjukhuet Uppsala

    Uppsala, Region Uppsala, 75185, Sweden

  • Ersta sjukhus

    Stockholm, Stockholm County, 11691, Sweden

  • Hospital Sønderjylland

    Aabenraa, 6200, Denmark

  • Höglandssjukhuset Eksjö

    Eksjö, Region Jönköpings Län, 57581, Sweden

  • Karolinska Universitetssjukhuset

    Stockholm, Region Stockholm, 17176, Sweden

  • Landspitali

    Reykjavik, 101, Iceland

  • OUH Svendborg Hospital

    Svendborg, 5700, Denmark

  • Odense University Hospital

    Odense, 5000, Denmark

  • Oslo Universitetssykehus

    Oslo, 0424, Norway

  • Sykehuset i Telemark

    Skien, 3710, Norway

  • Sykehuset i Vestfold

    Tønsberg, 3103, Norway

  • Universitetssjukhuset i Linköping

    Linköping, Region Östergötland, 58185, Sweden

  • Universitetssjukhuset Örebro

    Örebro, Örebro County, 70185, Sweden

  • Vestre Viken HF

    Drammen, 3004, Norway

  • Østfold Kalnes

    Grålum, 1714, Norway

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