Blood test could guide smarter IBD treatment from day one

NCT ID NCT05180175

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 28 times

Summary

This study tested whether a blood test measuring proteins can help doctors choose a more powerful treatment early for people newly diagnosed with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. 300 patients were split into two groups: one where doctors saw the protein test results and used a top-down treatment plan (starting with strong drugs like anti-TNF), and another where doctors followed standard care. The goal was to see if the protein-guided approach leads to better disease control and remission without long-term steroids.

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Contacts and locations

Locations

  • Akademiska Sjukhuet Uppsala

    Uppsala, Region Uppsala, 75185, Sweden

  • Ersta sjukhus

    Stockholm, Stockholm County, 11691, Sweden

  • Hospital Sønderjylland

    Aabenraa, 6200, Denmark

  • Höglandssjukhuset Eksjö

    Eksjö, Region Jönköpings Län, 57581, Sweden

  • Karolinska Universitetssjukhuset

    Stockholm, Region Stockholm, 17176, Sweden

  • Landspitali

    Reykjavik, 101, Iceland

  • OUH Svendborg Hospital

    Svendborg, 5700, Denmark

  • Odense University Hospital

    Odense, 5000, Denmark

  • Oslo Universitetssykehus

    Oslo, 0424, Norway

  • Sykehuset i Telemark

    Skien, 3710, Norway

  • Sykehuset i Vestfold

    Tønsberg, 3103, Norway

  • Universitetssjukhuset i Linköping

    Linköping, Region Östergötland, 58185, Sweden

  • Universitetssjukhuset Örebro

    Örebro, Örebro County, 70185, Sweden

  • Vestre Viken HF

    Drammen, 3004, Norway

  • Østfold Kalnes

    Grålum, 1714, Norway

Conditions

Explore the condition pages connected to this study.