Could a common pill boost biologic therapy for ulcerative colitis?
NCT ID NCT05205603
First seen May 06, 2026 · Last updated May 06, 2026 · Updated 1 time
Summary
This study looked at whether adding mesalazine (a standard anti-inflammatory drug) to biologic treatments like vedolizumab or infliximab can improve healing of the colon lining in people with moderate to severe ulcerative colitis. 438 adults took part. The main goal was to see if more patients achieved endoscopic remission (a healed gut lining) after 12 months with the combination therapy compared to biologics alone.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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First Affiliated Hospital of Shantou University Medical College
Shantou, Guangdong, China
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First People's Hospital of Foshan
Guangzhou, Guangdong, China
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General Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, China
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Guangzhou Panyu Central Hospital
Guangzhou, Guangdong, China
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Nanhai Hospital, Southern Medical University
Guangzhou, Guangdong, China
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People's Hospital of Chongqing
Chongqing, Chongqing Municipality, China
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Shengjing Hospital
Shenyang, Liaoning, China
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Shunde Hospital of Southern Medical University
Guangzhou, Guangdong, China
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The Second Affiliated Hospital of Dalian Medical University
Dalian, Liaoning, China
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Zhejiang University
Hanzhou, Zhejiang, China
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the Sixth Affiliated Hospital of Sun Yat-Sen University
Guangzhou, Guangdong, 501655, China
Conditions
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