PREDIABETES

This study is testing whether a 12-week virtual group exercise program called Vivo can help improve leg strength and lower blood sugar levels in older adults with prediabetes. Participants are sedentary men and women aged 60 and older. They are randomly assigned to either join th…

This study aimed to see if metformin, a common diabetes medication, could improve blood vessel function in people with prediabetes. Researchers planned to compare metformin against a placebo pill over 12 weeks in 30 participants. The goal was to understand if early treatment coul…

This study is testing whether eating dried Saskatoon berries daily can help people with prediabetes or newly diagnosed type 2 diabetes. Researchers will compare the effects of the berries against dried apples over 12 weeks in 92 participants. The main goal is to see if the berrie…

This small pilot study is testing whether a simple home exercise program, with or without a vitamin B3-like supplement, is a practical way to help adult survivors of childhood cancer who have prediabetes. The goal is to see if this approach can improve muscle health and how the b…

This study aims to see if dentists can help find undiagnosed high blood sugar by adding a simple finger-prick test during routine gum disease exams. It will involve 300 adults with advanced gum disease. The goal is to identify people who might have diabetes or prediabetes without…

This study is testing whether portable ultrasound and blood glucose monitoring devices can help doctors detect chronic conditions like diabetes and heart disease earlier than standard care. 200 participants at risk for these conditions will use the devices at home for 6 months wh…

This study is testing whether artificial intelligence (AI) software can reliably analyze pictures of the back of the eye to find early signs of diabetic retinopathy, a common diabetes complication that can lead to vision loss. Researchers are enrolling 100 adults with prediabetes…

This study is testing two simple, low-cost programs to help people with prediabetes start treatments known to prevent type 2 diabetes. It involves 960 adults from primary care clinics. The programs use a decision aid or text messages to encourage people to begin a lifestyle chang…

This study is testing whether a probiotic supplement can work as well as the standard medication metformin to help people with prediabetes. It aims to prevent or delay the development of type 2 diabetes by improving the body's blood sugar control and insulin sensitivity. A small …

This large study is testing whether berberine, a compound from plants, can help prevent heart disease and type 2 diabetes in adults at high risk. Over 2,000 participants in China will take either berberine or a placebo pill for three years, alongside lifestyle advice. Researchers…

This study is testing whether adding a CPAP breathing machine to a standard diet and exercise program can better prevent diabetes in overweight adults with prediabetes and sleep apnea. Researchers want to see if treating sleep apnea improves blood sugar and heart health more than…

This study is testing if a medication called empagliflozin, already used to treat type 2 diabetes, can help people with prediabetes. Researchers want to see if taking the drug for 13 weeks improves how the body handles blood sugar in 60 overweight or obese adults. The goal is to …

This study is testing if pharmacists can help prevent diabetes in hospitality workers in New Orleans. It will check how many workers are at risk and then offer them education sessions, wellness tools like fitness trackers, and connections to health programs. The goal is to see if…

This study is testing whether adding supervised cycling and rowing exercise to a Mediterranean-style diet improves blood sugar control in women with prediabetes better than the diet alone. Researchers will follow 30 women for 12 weeks, using continuous glucose monitors to track d…

This study is testing if adding two extra supports helps people stick with a proven diabetes prevention program. Low-income adults with prediabetes will either join the standard program or the program plus a peer buddy and chances to earn healthy food vouchers. Researchers will s…

This study is testing whether a combination of a common diabetes prevention drug (metformin) and a digital lifestyle coaching program can help prevent adult survivors of childhood cancer from developing full diabetes. The main goal is to see if this combined approach is safe and …

This study aims to understand why whole wheat bread helps lower blood sugar for some people with prediabetes but not others. Researchers are comparing the effects of eating whole wheat bread versus white bread for two weeks at a time in 65 adults with prediabetes. They will colle…

This study aims to find out if people with prediabetes or type 2 diabetes need to push themselves hard during weight training to see better blood sugar control, or if lighter effort works just as well. Fifteen participants will try three different sessions: a high-effort workout,…

This study aimed to learn if exercising in the morning or evening is better for improving the body's blood sugar control in adults with prediabetes and obesity. It planned to have participants complete short periods of morning exercise, evening exercise, and no exercise while clo…

This project is not a new treatment trial, but a large-scale analysis of past research. Researchers are compiling and reviewing results from many existing diet studies to understand if replacing animal protein (like meat and dairy) with plant protein (like beans and nuts) leads t…