PREDIABETES

This study tests whether eating dried whole Saskatoon berries can improve blood sugar and cholesterol levels in adults with untreated prediabetes or early type 2 diabetes. About 92 participants will eat either Saskatoon berries or a control dried fruit daily for 10 weeks. Researc…

This study tests whether empagliflozin, a drug used for type 2 diabetes, can improve blood sugar control in 60 overweight or obese adults with prediabetes. Participants will take the drug or a placebo for 13 weeks. The goal is to see if the drug helps the body use sugar better an…

This study aimed to see if metformin improves blood vessel function in adults aged 18-55 with prediabetes. Participants would have taken metformin or a placebo for 12 weeks. However, the study was withdrawn before enrolling anyone, so no results are available.

This study tests different weight loss plans for 30 adults with prediabetes and physical disabilities. Participants first try either a high or low carbohydrate diet. After 4 weeks, those who lose less than 2.5% of their body weight get extra help, like exercise coaching or time-r…

This study tests if probiotics can help control blood sugar in people with prediabetes as well as the standard drug metformin. About 30 adults aged 31-60 with prediabetes will take either probiotics or metformin for 13 weeks. The goal is to see which approach better improves bloo…

This study looks at adding a quick blood sugar test to regular dental check-ups for people with advanced gum disease. The goal is to find undiagnosed high blood sugar or diabetes and see how patients and dentists feel about this approach. About 300 adults with severe gum disease …

This study tests whether portable devices like handheld ultrasound and blood glucose monitors can help doctors find chronic diseases earlier than standard care. Two hundred adults aged 18 to 75 with conditions like prediabetes or high blood pressure will use the devices or receiv…

This study tests whether berberine, a natural compound, can prevent heart disease and diabetes in 2024 adults with prediabetes, obesity, and other risk factors. Participants take berberine or a placebo for one year, and researchers track changes in blood sugar and cholesterol. Th…

This study tests whether adding a support buddy and healthy food vouchers to a standard diabetes prevention program helps low-income adults with prediabetes stick with healthy habits and lower their risk of developing diabetes. About 142 participants will be split into two groups…

This study tests whether a combination of the diabetes drug metformin and a digital lifestyle program can prevent diabetes in adult survivors of childhood cancer who have prediabetes. About 96 participants will first try lifestyle changes alone for 12 weeks, then add metformin fo…

This study tests whether simple reminders and encouragement (behavioral nudges) can help adults with prediabetes take proven steps to prevent diabetes, such as joining a lifestyle program or taking metformin. About 960 English- or Spanish-speaking adults aged 18-80 with prediabet…

This study looks at whether adding supervised cycling and rowing to a Mediterranean diet helps women with prediabetes control their blood sugar better than diet alone. About 30 women will be split into three groups based on their current blood sugar levels. They will follow the d…

This study tests a new tool that helps doctors have better conversations with patients who have prediabetes. The tool uses a questionnaire to understand how ready a patient is to make healthy changes, then suggests resources like health coaches or diabetes prevention programs. Ab…

This study looks at whether adding CPAP (a machine that helps you breathe during sleep) to a lifestyle program can improve blood sugar and blood pressure more than lifestyle changes alone. Researchers are studying 174 overweight or obese adults with prediabetes and sleep apnea. T…

This study looks at whether pharmacists can help hospitality workers in New Orleans avoid diabetes. About 300 adults who work in hotels, restaurants, or similar jobs and are at risk for prediabetes will take part. They will attend lifestyle education sessions, get wellness tools …

This study looks at whether the amount of effort during weightlifting changes blood sugar levels in people with prediabetes or type 2 diabetes. Fifteen adults will try a high-effort workout, a low-effort workout, and a rest day to compare blood sugar and how they feel. The goal i…

This study aimed to see if adding pramlintide to semaglutide changes appetite and eating habits in people with obesity and prediabetes. It also looked at whether tests before treatment could predict who responds best. The study was withdrawn before enrolling anyone, so no results…

This study uses artificial intelligence to examine the eyes of 100 adults with prediabetes or diabetes for early signs of diabetic retinopathy, a condition that can lead to vision loss. Participants undergo retinal imaging with both stationary and mobile cameras, and an AI algori…

This study looks at how eating whole wheat bread changes gut bacteria and health markers in adults with prediabetes. Over two weeks, 65 participants will eat either whole wheat or white bread daily, then provide stool, urine, and blood samples. The goal is to understand how whole…

This study is a review of many smaller studies that looked at what happens when people replace animal proteins (like meat, dairy, and eggs) with plant proteins (like beans, nuts, and seeds). The goal is to see if this simple swap can improve blood sugar, cholesterol, blood pressu…

This study screened over 16,600 adults in Spain (ages 45-70) with at least one risk factor (like high blood pressure or smoking) but no known heart disease. Half received advanced ultrasound and urine tests to find hidden artery and kidney problems. The goal is to see if early de…

This study looked at whether exercising in the morning or evening changes how the body handles sugar in adults with prediabetes. Participants completed short periods of no exercise, morning exercise, and evening exercise while their blood sugar, sleep, and activity were tracked. …

This study looks at whether a program of exercise and a dietary supplement called nicotinamide riboside (similar to vitamin B3) can improve muscle health and insulin resistance in adults who survived childhood cancer and now have prediabetes. About 20 participants will take part …

This study looks at whether older adults with prediabetes have slower brain energy use and thinking speed compared to those with normal blood sugar. It also tests if a single dose of a ketone supplement can temporarily improve brain function. Twenty veterans aged 60-75 will under…