Could a TB vaccine stop diabetes? new trial hopes so
NCT ID NCT05591339
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the BCG vaccine, normally used for tuberculosis, can prevent type 2 diabetes in people with pre-diabetes. Researchers in Guinea-Bissau will give two doses of BCG or a placebo to 200 adults and track their blood sugar levels. The goal is to see if the vaccine reduces inflammation and insulin resistance, potentially stopping pre-diabetes from becoming full-blown diabetes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BCG vaccine
- What this could lead to
- If it works, this could point toward a low-cost way to prevent type 2 diabetes in at-risk populations.
- What could go wrong
- This is a small, early-phase trial in one country, so results may not apply elsewhere. The BCG vaccine can cause local reactions and is not proven for diabetes prevention.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bandim Health Project
Bissau, 1004, Guinea-Bissau
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