PREDIABETES

This study aims to see if replacing typical high-fat, high-sugar snacks with a daily serving of pecans can improve blood sugar control and heart health in people with prediabetes. About 150 adults will be randomly assigned to either eat 1.5 ounces of pecans daily for 16 weeks or …

This study is testing if using a specific type of cooking oil, called diacylglycerol (DAG) oil, for four weeks can help control blood sugar and improve health in middle-aged and older adults with prediabetes. Participants will replace their usual cooking oil with either DAG oil o…

This trial tests whether using diabetes medications can reverse prediabetes back to normal blood sugar levels in people who also have heart disease. It will enroll 158 adults to see if this early treatment can prevent diabetes-related complications like eye, kidney, and nerve dam…

This study is testing whether a daily probiotic capsule can help improve cholesterol, blood sugar control, and thinking skills in adults with prediabetes or diabetes. Researchers will enroll 210 people to take either the probiotic or a placebo pill for 12 weeks. The goal is to se…

This small pilot study is testing if adding a drug called bromocriptine is safe and can help control blood sugar problems in people with schizophrenia. The blood sugar issues are a serious side effect of common antipsychotic medications and can lead to diabetes. The study will in…

This study is testing whether a program using smartwatches, a phone app, and health coaching can help overweight adults improve their heart health. It will involve about 1,400 people who have borderline high blood pressure, blood sugar, or cholesterol. The goal is to see if this …

This study aims to find better ways to get people with prediabetes to join and stay in a diabetes prevention program at local health centers. Researchers will test new support systems like training for staff and reminders for patients to see if they improve participation and heal…

This study is testing whether a digital support group can help people with prediabetes make lasting healthy lifestyle changes to prevent type 2 diabetes. About 146 adults in China will be randomly assigned to either use a special app with health education and group support or rec…

This study is testing whether taking a weekly vitamin D supplement, with the dose adjusted to reach a specific target level in the blood, can help control blood sugar in adults who are at high risk of developing type 2 diabetes. One hundred adults with prediabetes will be randoml…

This study aims to see if a healthy Mediterranean diet that includes one medium potato per day works just as well as a potato-free version for lowering diabetes and heart disease risk in adults with prediabetes. About 74 participants will be randomly assigned to follow one of the…

This study aims to find people at high risk for developing diabetes much earlier than current tests allow. Researchers will use wearable glucose monitors and artificial intelligence to analyze data from 1,000 healthy adults. The goal is to create a smarter system that can spot wa…

This study explores whether wearing a continuous glucose monitor (CGM) can motivate people with prediabetes to be more physically active. Researchers want to see if real-time blood sugar feedback encourages lifestyle changes, like walking more, to help prevent the development of …

This study is testing if adding a continuous glucose monitor (CGM) to a proven lifestyle coaching program helps people with prediabetes stick to healthy habits. The CGM gives real-time feedback on how food and activity affect blood sugar. Researchers will see if this tech-boosted…

This study aims to understand how consuming different artificial and natural sweeteners affects people with prediabetes, a condition of high blood sugar that increases the risk of type 2 diabetes and heart disease. Researchers will enroll 80 participants with prediabetes and have…

This study aims to better understand prediabetes in young adults by observing how it relates to other health issues like high cholesterol and fatty liver. Researchers will collect health data from 120 adults with prediabetes at a single hospital. The goal is to identify patterns …

This study is testing how easy it is to use a new wrist-worn device called the Argus CGM. The device uses light sensors and artificial intelligence to estimate blood sugar levels without needing to prick the skin. About 100 adults with type 1 diabetes, type 2 diabetes, or prediab…

This study aims to learn if exercising at a specific time of day—morning or evening—works better for improving how the body handles sugar in adults with prediabetes who have extreme natural body clocks (early 'larks' or late 'owls'). Researchers will compare no exercise, morning …

This study aims to understand how exercise helps the body process sugar and fat by looking at tiny communication packages sent from muscles to fat cells. Researchers will recruit 80 adults, half with prediabetes and half without, to perform resistance exercise and provide small t…

This study aims to understand how prediabetes affects blood vessels early on, before full diabetes develops. Researchers will use a new, high-resolution ultrasound to measure the thickness of artery walls in 1740 adults with prediabetes. The goal is to gather knowledge that could…