PREDIABETES

This study looks at whether adding one medium potato a day to a healthy Mediterranean diet changes blood sugar and heart disease risk in adults with prediabetes. About 74 participants will follow either a diet with or without potatoes for 12 weeks. The goal is to see if potatoes …

This study tests whether replacing regular cooking oil with diacylglycerol (DAG) oil for four weeks can improve blood sugar control and metabolism in 40 middle-aged and older adults with prediabetes. Participants will either use DAG oil or canola oil while keeping their usual lif…

This study looks at whether eating proteins and vegetables before carbohydrates can improve blood sugar control in adults with diabetes or prediabetes who also experience food insecurity. Participants will receive free produce boxes and either standard nutrition advice or extra c…

This study looks at whether eating pecans instead of snacks high in bad fats and sugar can improve blood sugar control and heart health in people with prediabetes. About 147 adults aged 25-65 with prediabetes will be split into two groups: one eats 1.5 ounces of pecans daily for …

This study tests whether a daily probiotic called LP-LDL® can improve cholesterol, blood sugar, and thinking skills in 210 adults with prediabetes or diabetes (type 1 or 2) who also have high cholesterol or triglycerides. Participants will take either the probiotic or a placebo f…

This study tests whether glucose-lowering medications (semaglutide and dapagliflozin) can reverse prediabetes and prevent early diabetes complications in people with heart disease. About 158 participants with prediabetes and coronary artery disease will receive either the drugs p…

This small pilot study will test the safety and tolerability of bromocriptine, a drug used for other conditions, in 15 adults with schizophrenia who also have prediabetes (higher than normal blood sugar). The goal is to see if bromocriptine can help prevent or delay type 2 diabet…

This study looks at whether wearing a continuous glucose monitor (CGM) can help people with prediabetes become more physically active and prevent type 2 diabetes. About 50 adults with prediabetes will wear a CGM for 20 days and receive education on their blood sugar levels. The g…

This study looks at ways to make a diabetes prevention program work better in district health centres. Researchers will test tools like patient engagement systems and staff training to see if they help more people with prediabetes join and stay in the program. The goal is to impr…

This study tests whether weekly vitamin D supplements, adjusted to reach a specific blood level, can improve blood sugar control in 100 adults aged 30-74 with prediabetes. Participants are randomly assigned to vitamin D or placebo for 18 months, with dose adjustments based on blo…

This study tests whether a virtual health community can help adults with prediabetes improve blood sugar control and prevent type 2 diabetes. Participants will receive lifestyle education, guidance, and group support through a digital platform for 6 months. The goal is to see if …

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect heart disease risk factors in 80 adults with prediabetes. Participants will be randomly assigned to consume one sweetener or water for two weeks. Researchers will measure ch…

This study is testing a new, noninvasive device called the Argus CGM that uses light and AI to estimate blood sugar levels without needles. Up to 100 adults with type 1 diabetes, type 2 diabetes, or prediabetes will wear the device for 15 days while researchers collect data to im…

This study looks at whether exercising in the morning or evening improves how the body handles sugar in people with prediabetes who have an extreme natural body clock. Twenty-eight overweight adults will try no exercise, morning exercise, and evening exercise on separate days. Th…

This study aims to understand prediabetes in young adults and how it relates to other health issues like insulin resistance, high cholesterol, and fatty liver. Researchers will study 120 people with prediabetes at Assiut University Hospital through exams and lab tests. The goal i…

This study looks at how muscle cells send tiny packages called extracellular vesicles to fat cells during exercise, which may affect how the body handles sugar and fat. Researchers will compare 80 adults with and without prediabetes to understand why some people respond better to…

This study uses a special high-frequency ultrasound to look at the walls of arteries in people with prediabetes. The goal is to detect very early signs of blood vessel damage that standard tests might miss. Researchers will measure the thickness of artery layers in 1,740 adults t…

This study aims to find better ways to identify people at high risk for prediabetes using continuous glucose monitors (CGMs) and artificial intelligence (AI). Researchers will enroll 1000 adults aged 35 and older with a high diabetes risk score but normal blood sugar levels. By a…