Prediabetes reversal hope: new drug combo tested in major trial

NCT ID NCT07558525

First seen May 13, 2026 · Last updated May 13, 2026

Summary

This study tests whether a medication called chiglitazar sodium, combined with healthy lifestyle changes, can help people with prediabetes return to normal blood sugar levels. About 472 adults with prediabetes will take either the drug or a placebo for 52 weeks, while all follow a lifestyle program. The main goal is to see how many achieve normal glucose metabolism by week 64, and to monitor for side effects and progression to type 2 diabetes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tsinghua Changgung Hospital

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Changsha Eighth Hospital

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chengdu First People's Hospital

    Chengdu, Sichuan, 610499, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emergency General Hospital

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Heji Hospital Affiliated to Changzhi Medical College

    Changzhi, Shanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Loudi Central Hospital

    Loudi, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • People's Hospital of Hunan Province

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Quanzhou First Hospital, Fujian

    Quanzhou, Fujian, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Ninth People's Hospital

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shenzhen Bao'an People's Hospital

    Shenzhen, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shenzhen Bao'an Traditional Chinese Medicine Hospital

    Shenzhen, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital

    Chengdu, Sichuan, 610072, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sir Run Run Hospital, Nanjing Medical University

    Nanjing, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Central Hospital of Xiangtan

    Xiangtan, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Central Hospital of Yongzhou

    Yongzhou, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Guangzhou Medical University

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Henan University of Science & Technology

    Luoyang, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Harbin

    Harbin, Heilongjiang, 150010, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First People's Hospital of Changde City

    Changde, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Harbin Medical University

    Harbin, Heilongjiang, 150086, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Second Xiangya Hospital, Central South University

    Changsha, Hunan, 410011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • The Southwest Hospital of the Army Medical University

    Chongqing, 400038, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Third People's Hospital of Chengdu

    Chengdu, Sichuan, 610036, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Third Xiangya Hospital of Central South University

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tongji Hospital of Tongji University

    Shanghai, China

  • Xuanwu Hospital Capital Medical University

    Beijing, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yueyang People's Hospital

    Yueyang, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhongnan Hospital of Wuhan University

    Wuhan, Hubei, 430071, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.