Can exercise and a B3 supplement help cancer survivors fight prediabetes?
NCT ID NCT05023993
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study looks at whether a home exercise program plus a dietary supplement called nicotinamide riboside (similar to vitamin B3) can improve muscle health and insulin resistance in adult survivors of childhood cancer who have prediabetes. The study will enroll 20 people and mainly checks if the program is practical and doable. If successful, it may lead to larger studies on managing metabolic health in this group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nicotinamide riboside (a dietary supplement similar to vitamin B3) and a home exercise program
- What this could lead to
- If this small pilot works, it could point toward a way to help childhood cancer survivors manage prediabetes and improve muscle health.
- What could go wrong
- This is a very early, small study (20 people) testing feasibility, not effectiveness. The supplement and exercise may not improve health outcomes, and results may not apply to all survivors.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
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