MECHANICAL VENTILATION
Clinical trials for MECHANICAL VENTILATION explained in plain language.
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Zapping muscles to free patients from breathing machines
Disease control CompletedThis study tested whether gentle electrical stimulation of breathing muscles could help patients who have been on a ventilator for at least 3 weeks breathe on their own faster and more successfully. Researchers compared different stimulation methods (targeting the diaphragm or ab…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Capital Medical University • Aim: Disease control
Last updated Apr 02, 2026 02:12 UTC
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Personalized breathing support aims to protect lungs in High-Risk surgery
Disease control CompletedThis study tested if customizing ventilator pressure during surgery is better than using a standard setting for obese patients having spinal surgery. It involved 80 patients to see if the personalized approach improved oxygen levels during the operation and reduced breathing prob…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Konya City Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Smart device tested to protect Kids' airways in ICU
Disease control CompletedThis study compared two methods for managing the pressure in breathing tubes for children on ventilators in intensive care. It tested whether an automatic monitoring device works better than nurses manually checking every few hours. The goal was to see if the automatic method kee…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Dr. Behcet Uz Children's Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Breathing machine study aims to prevent heart damage in critically ill patients
Disease control CompletedThis study compared two different ways to set a breathing machine for patients with severe lung failure (ARDS). The goal was to see which method is better at protecting the right side of the heart from damage, a common and dangerous complication. Researchers randomly assigned 60 …
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: XiaoJing Zou,MD • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New ventilator coach aims to shield lungs in critical care
Disease control CompletedThis study tested a new ventilator guidance system called VentCoach, designed to better protect patients' lungs while they are on breathing machines in the intensive care unit. Researchers compared VentCoach to the standard ventilator settings currently used in the hospital. The …
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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Tying down ICU patients less often may fight dangerous confusion
Disease control CompletedThis study tested whether using wrist restraints only when absolutely necessary, rather than as a standard practice, could help reduce the duration of delirium (a serious state of confusion) in intensive care unit (ICU) patients on breathing machines. 423 adult patients expected …
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Mar 05, 2026 13:59 UTC
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Breathing machine test could prevent unnecessary IV fluids in ICU
Diagnosis CompletedThis study tested a simple method to predict if critically ill patients on breathing machines will benefit from receiving IV fluids. Doctors temporarily adjusted a ventilator setting to see if it mimicked the effect of giving fluids. The goal was to find a quick test to avoid giv…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Mar 23, 2026 15:19 UTC
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Nighttime drug combo tested to help critically ill patients sleep better
Symptom relief CompletedThis study tested whether giving a combination of two low-dose sedative drugs at night could improve sleep quality for patients in the intensive care unit (ICU) who need help breathing. Researchers enrolled 174 patients aged 50 or older who were on a ventilator or high-flow oxyge…
Matched conditions: MECHANICAL VENTILATION
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Apr 02, 2026 02:11 UTC
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Could a simple change in how doctors remove breathing tubes help patients breathe easier after surgery?
Symptom relief CompletedThis study tested if removing a patient's breathing tube using a specific 'positive pressure' technique could help prevent low oxygen levels after major abdominal surgery. Researchers compared this new method to the standard way of removing the tube in 208 adult patients. The goa…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Mar 06, 2026 15:38 UTC
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Breakthrough study aims to cut powerful painkiller use in ICU
Symptom relief CompletedThis study tested if a non-opioid drug called nefopam, given through a continuous IV drip, could safely reduce the need for strong opioid painkillers in critically ill adults on breathing machines. Researchers compared the drug to standard pain care in 60 patients to see if it lo…
Matched conditions: MECHANICAL VENTILATION
Phase: PHASE3 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Mar 02, 2026 15:29 UTC
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Breathing machine vs. hand pump: which is safer for moving critical patients?
Knowledge-focused CompletedThis study compared two ways to help patients breathe while being moved from the operating room to the intensive care unit after major heart surgery. Researchers looked at whether using a portable breathing machine or a manual hand-pumped bag was better at keeping patients' oxyge…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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New tool aims to ease tough choices for families of critically ill patients
Knowledge-focused CompletedThis study tested a new online tool called TRACH-Support, designed to help families and medical teams make difficult decisions about long-term breathing support for patients who cannot breathe on their own. Over 100 family members and healthcare providers reviewed the tool and sh…
Matched conditions: MECHANICAL VENTILATION
Sponsor: Denver Health and Hospital Authority • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Researchers shed light on the hidden struggles of ventilator weaning
Knowledge-focused CompletedThis study observed 156 critically ill patients in the ICU who were slowly taken off a breathing machine (ventilator) using a tracheostomy tube in their neck. The goal was to understand how long this weaning process takes and how often patients experience breathing difficulty, di…
Matched conditions: MECHANICAL VENTILATION
Sponsor: Henrik Endeman • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Doctors probe hidden pressures inside patients on breathing machines
Knowledge-focused CompletedThis study aimed to better understand how different settings on a surgical breathing machine affect pressure inside a patient's chest. Researchers observed 150 adult patients during elective surgery to see how changing air volume and pressure impacted internal chest pressure and …
Matched conditions: MECHANICAL VENTILATION
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Doctors review past cases to see if new sedation gas helps kids in ICU
Knowledge-focused CompletedThis study looked back at the medical records of 50 children who were on breathing machines in intensive care. Researchers wanted to see if using inhaled anesthetic gases for long-term sedation helped reduce the need for other strong sedative and pain medications. The goal was to…
Matched conditions: MECHANICAL VENTILATION
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Ventilator weaning may shift eye pressure, study finds
Knowledge-focused CompletedThis study aimed to understand how switching from a breathing machine to breathing on their own affects pressure inside the eye for intensive care patients. Researchers observed 40 adult patients in the ICU, measuring their eye pressure before and after this breathing transition.…
Matched conditions: MECHANICAL VENTILATION
Sponsor: Sevim Şenol Karataş • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Doctors watch how ventilator settings affect brain injury recovery
Knowledge-focused CompletedThis study observed how doctors in intensive care units set ventilators for patients with serious brain injuries. Researchers tracked over 2,200 patients to see if different ventilator settings were linked to better or worse recovery six months later. The goal was to gather infor…
Matched conditions: MECHANICAL VENTILATION
Sponsor: University of Milano Bicocca • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Doctors search for safer breathing settings during common surgeries
Knowledge-focused CompletedThis study observed patients during laparoscopic (keyhole) abdominal surgery to compare two different pressure settings on the breathing machine. Researchers wanted to see how these settings affect the amount of energy delivered to the lungs and the patient's oxygen levels. The g…
Matched conditions: MECHANICAL VENTILATION
Sponsor: Kocaeli City Hospital • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Can a Machine's 'Sigh' unlock better breathing for ICU patients?
Knowledge-focused CompletedThis study tested a new method to help doctors fine-tune ventilator settings for critically ill patients. Researchers wanted to see if a special, deep 'sigh' breath programmed into the ventilator could provide a clearer picture of how stiff or flexible a patient's lungs are. This…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: AUSL Romagna Rimini • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:28 UTC
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Doctors use ultrasound to watch breathing muscle in ICU
Knowledge-focused CompletedThis study aimed to understand how a patient's main breathing muscle, the diaphragm, changes when a breathing machine is set to different modes. Researchers used ultrasound to measure diaphragm thickness in 66 ICU patients on ventilators, comparing machine-controlled breathing to…
Matched conditions: MECHANICAL VENTILATION
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Doctors study which tracheostomy method is safer for breathing
Knowledge-focused CompletedThis study looked back at medical records to compare two different guidance methods used during a common ICU procedure to insert a breathing tube (tracheostomy). It involved 77 adult patients who were on ventilators. The goal was to see if using an ultrasound or a small camera (b…
Matched conditions: MECHANICAL VENTILATION
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:26 UTC
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Researchers tweak baby ventilator knobs to find gentler breathing support
Knowledge-focused CompletedThis study looked at how adjusting a specific setting on breathing machines (ventilators) affects newborns with respiratory distress. Doctors tested different 'pressure rise time' settings on 17 stable infants in intensive care to see how it changed their breathing patterns and m…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:25 UTC
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Breathing tube could hold key to easier ventilator monitoring
Knowledge-focused CompletedThis study aimed to see if measuring pressure changes in the cuff of a breathing tube could be used instead of a more complex and uncomfortable procedure to monitor how hard a patient on a ventilator is trying to breathe. Researchers compared the two methods in 30 stable, critica…
Matched conditions: MECHANICAL VENTILATION
Phase: NA • Sponsor: Jian-Xin Zhou • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:25 UTC