MECHANICAL VENTILATION

This study is testing a new device designed to automatically keep the pressure in a breathing tube at the right level. It will compare this device to the usual method where nurses manually check and adjust the pressure. The goal is to see if the automatic device better prevents s…

This large study aims to determine whether the specific setting used on breathing machines (ventilators) affects how quickly critically ill patients recover and survive. Researchers will test three different ventilator modes across multiple hospital intensive care units, involvin…

This study aims to find the best way to prevent lung collapse in adults having lower back surgery while lying face-down under general anesthesia. Researchers will compare doing a special breathing maneuver just once at the start of surgery to doing it repeatedly every hour during…

This study tests whether giving children an amino acid infusion during and after heart surgery can help prevent serious kidney injury and reduce time on a breathing machine. Researchers will compare the amino acid treatment to a placebo in 30 children at high risk for these compl…

This study is testing whether adding warm, sterile fluid into the womb during labor can help protect newborns from serious breathing problems. It will enroll 320 pregnant people who have thick meconium (baby's first stool) in their amniotic fluid, which can cause breathing issues…

This study aims to see if a special ultrasound scan can predict which critically ill patients will struggle to breathe on their own after being taken off a ventilator. Doctors will scan 350 ICU patients before a breathing test to see if signs of fluid overload in the veins predic…

This study is testing a new, personalized method to prevent pneumonia in critically ill patients on breathing machines in the ICU. Researchers will use a rapid test to analyze the bacteria in a patient's airway. If harmful bacteria are found, the patient receives a targeted inhal…

This study is testing if adding a low-dose ketamine infusion to standard sedation helps adult patients in the intensive care unit (ICU) who are on breathing machines. Researchers want to see if ketamine can reduce delirium, lower the need for other strong pain and sedative drugs,…

This study aims to find a better way to predict when patients in intensive care can safely stop using a ventilator. Researchers will use ultrasound to measure how a patient's main breathing muscle (the diaphragm) moves. By observing 100 patients, they hope to find a measurement t…

This study aims to learn if a specific method of adjusting breathing machine pressure helps children recovering from heart surgery. Researchers will compare 80 children who receive this pressure adjustment technique to those who receive standard care. The goal is to see if this a…

This study aims to understand how different pressure settings on a breathing machine affect blood flow congestion in the body's veins for patients with severe lung failure (ARDS). Researchers will look back at medical records and ultrasound scans from about 30 critically ill pati…

This study aims to better understand how the lungs work in brain-injured patients who are trying to come off a breathing machine (ventilator). Researchers will use a special belt with electrodes to take pictures of air movement in different parts of the lungs. The goal is to see …

This study looks back at medical records to understand how nutrition therapy affects patients who need breathing machines in intensive care. Researchers will analyze data from 2,000 adults to see if personalized nutrition support can improve survival rates and shorten hospital st…