Simple ultrasound may predict ventilator weaning failure in ICU patients

NCT ID NCT07343882

Not yet recruiting Knowledge-focused Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special ultrasound technique, called VExUS, can predict which ICU patients will have trouble breathing on their own after being on a ventilator. Researchers will scan the veins of 350 patients just before a breathing trial. The goal is to see if signs of fluid congestion can forecast failure, helping doctors intervene earlier. The study is observational and offers no direct benefit to participants, but could improve care for future patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could give doctors a simple, non-invasive tool to predict which patients will struggle to come off a ventilator, potentially reducing ICU stays and complications.
What could go wrong: This is an early observational study, not a treatment trial. It only tests if the ultrasound method can predict failure—it does not test any new therapy. Results may not change practice immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary edema VEXAS syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION POCUS PULMONARY EDEMA - ACUTE VEXUS WEANING FAILURE

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