New device aims to prevent pneumonia in ventilator patients

NCT ID NCT06848010

Not yet recruiting Disease control Sponsor: Policlinico Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a device that automatically monitors and adjusts the pressure of the cuff on a breathing tube, keeping it at a steady 25 cmH2O. The goal is to see if this reduces leaks of fluids into the lungs, which can cause pneumonia. About 54 critically ill patients on ventilators will be randomly assigned to either the automatic device or standard manual checks every 8 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Automated endotracheal cuff controller (device)
What this could lead to: If it works, this device could help prevent ventilator-associated pneumonia by reducing fluid leaks into the lungs.
What could go wrong: This is a small, early-stage trial with only 54 patients, so results may not apply widely. The device may not reduce infections or could have technical issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pneumonia, Ventilator-Associated

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION PNEUMONIA, VENTILATOR-ASSOCIATED

Contacts and locations

Locations

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Milan, 20122, Italy

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