Simple swallow check may predict ventilator weaning failure

NCT ID NCT07659275

Not yet recruiting Knowledge-focused Sponsor: Universidade Federal de Pernambuco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a bedside tool called the APEX score, which evaluates swallowing biomechanics, to predict whether critically ill patients will need their breathing tube reinserted after planned removal. Researchers will enroll 800 adults on ventilators for at least 48 hours across multiple ICUs in Brazil. The goal is to see if adding this simple assessment to current checks can improve extubation decisions and reduce complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If the APEX score proves accurate, it could become a simple bedside tool to help doctors decide when it is safe to remove a breathing tube, potentially reducing complications.
What could go wrong: This is an observational study, not a treatment trial. The APEX score may not perform well across all patient groups or hospital settings, and it will not directly improve outcomes on its own.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS EXTUBATION FAILURE MECHANICAL VENTILATION

Contacts and locations

Locations

Hospital das Clínicas, Universidade Federal de Pernambuco

Recife, Pernambuco, Brazil

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