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Breathing breakthrough: safer ventilation during emergency surgery could save lives

NCT ID NCT03987789

Completed Disease control Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different ways of using a breathing machine during emergency abdominal surgery. One method used higher air pressure to keep the lungs open, while the other used lower pressure to avoid overstretching the lungs. The goal was to see which approach led to fewer lung complications and deaths after surgery. The study included 707 adults who needed emergency abdominal surgery lasting at least two hours.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMERGENCY ABDOMINAL SURGERY GENERAL ANESTHESIA MECHANICAL VENTILATION POSTOPERATIVE MORBIDITY

Contacts and locations

Locations

  • Assistance Publique-Hôpitaux de Marseille

    Marseille, France

  • Assistance Publique-Hôpitaux de Paris

    Paris, France

  • Hospital

    Annecy, France

  • Hospital

    Chalon-sur-Saône, France

  • Hospital

    Périgueux, France

  • Hospital

    Suresnes, France

  • Hospital

    Valenciennes, France

  • Institut Paoli Calmette

    Marseille, France

  • University Hospital

    Bordeaux, France

  • University Hospital

    Nantes, France

  • University hospital

    Angers, France

  • University hospital

    Besançon, France

  • University hospital

    Clermont-Ferrand, France

  • University hospital

    Dijon, France

  • University hospital

    Grenoble, France

  • University hospital

    Le Mans, France

  • University hospital

    Lille, France

  • University hospital

    Lyon, France

  • University hospital

    Marseile, France

  • University hospital

    Marseille, France

  • University hospital

    Montpellier, France

  • University hospital

    Nice, France

  • University hospital

    Nîmes, France

  • University hospital

    Pointe à Pitre, 97159, France

  • University hospital

    Rennes, France

  • University hospital

    Saint-Etienne, France

  • University hospital

    Strasbourg, France

  • University hospital

    Toulouse, France

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