Can a simple mesh stop hernias after emergency surgery?
NCT ID NCT07753551
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial tests whether placing a special mesh during emergency abdominal surgery can prevent incisional hernias, a common complication. Adults undergoing emergency midline laparotomy will be randomly assigned to receive either the mesh reinforcement or standard suture closure. The main goal is to compare the rate of hernias at one year after surgery, with additional monitoring of complications, pain, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A biosynthetic mesh (poly-4-hydroxybutyrate) placed during abdominal wall closure to reinforce the incision, compared with standard suture closure.
- What this could lead to
- If effective, this approach could reduce the risk of incisional hernias after emergency abdominal surgery, potentially improving recovery and quality of life for many patients.
- What could go wrong
- The trial is relatively small and results may not apply to all patients. Mesh placement could carry risks such as infection or increased pain, and the benefit may not be significant.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Policlinico di Roma Tor Vergata
Roma, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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