Could lidocaine replace opioids in emergency surgery recovery?

NCT ID NCT07262242

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two anesthesia methods for emergency abdominal surgery: one using the opioid fentanyl, and another using lidocaine to reduce opioid use. The goal is to see if the opioid-sparing approach leads to better recovery quality, fewer side effects like nausea and breathing problems, and less pain. The trial plans to enroll 120 adults aged 21-65 who need emergency laparotomy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine

What this could lead to

If it works, this could offer a safer pain control method for emergency abdominal surgery, reducing side effects and speeding recovery.

What could go wrong

This is a small, early-stage trial (120 people) that hasn't started yet. Lidocaine may not work as well as opioids for severe pain, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kasr Alainy Hospital

    Cairo, 11562, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••