New biomarker strategy aims to prevent failed breathing tube removals in ICU
NCT ID NCT05637099
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether repeated measurements of certain biomarkers during a spontaneous breathing trial can help predict which ICU patients will need to be re-intubated within 7 days. Researchers will follow 266 adults who have been on a ventilator for more than 48 hours and are ready to try breathing on their own. The goal is to improve decision-making and reduce complications from failed extubation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for EXTUBATION FAILURE are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Erasmus MC
Rotterdam, South Holland, 3015 GD, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple ultrasound predict which newborns breathe on their own?
- A Mother's voice as medicine? trial tests comforting effect on ventilated children
- Could lung fluid proteins reveal a new way to track severe lung injury?
- A simple cough measurement may help doctors decide when to safely remove a breathing tube
- Can inhaled sedation save money and improve outcomes for ventilated ICU patients?
- Brain waves reveal hidden effects of breathing machines on injured brains