New biomarker strategy aims to prevent failed breathing tube removals in ICU

NCT ID NCT05637099

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether repeated measurements of certain biomarkers during a spontaneous breathing trial can help predict which ICU patients will need to be re-intubated within 7 days. Researchers will follow 266 adults who have been on a ventilator for more than 48 hours and are ready to try breathing on their own. The goal is to improve decision-making and reduce complications from failed extubation.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Erasmus MC

    Rotterdam, South Holland, 3015 GD, Netherlands