New drug cocktail may help ICU patients get better sleep

NCT ID NCT05718024

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving a combination of two sedative drugs (dexmedetomidine and esketamine) at night can improve sleep quality for ICU patients who need a breathing tube or high-flow oxygen mask. The trial involved 174 adults aged 50 and older after surgery. Researchers measured sleep stages using brain wave monitoring to see if the drug combo helped patients spend more time in restorative sleep.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

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