Breathing settings during surgery may impact brain pressure, study finds

NCT ID NCT06979999

Completed Knowledge-focused Sponsor: Nigde Omer Halisdemir University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether applying extra breathing pressure (PEEP) during laparoscopic gallbladder surgery changes the size of the optic nerve sheath, which can indicate brain pressure. Researchers measured the nerve sheath with ultrasound at three points during surgery in 34 adult patients. The goal was to understand how breathing settings affect the brain during minimally invasive abdominal procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help anesthesiologists better manage breathing settings during surgery to protect the brain.
What could go wrong: This is a small, completed study with only 34 participants, so results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intracranial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACRANIAL PRESSURE MECHANICAL VENTILATION OPTIC NERVE SHEATH DIAMETER POSITIVE END-EXPIRATORY PRESSURE (PEEP)

Contacts and locations

Locations

Niğde Training and Research Hospital

Niğde, Niğde Province, 5200, Turkey (Türkiye)

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