INFERTILITY
Clinical trials for INFERTILITY explained in plain language.
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Scientists test new sperm selection technique to boost IVF success
Disease control CompletedThis study tested whether selecting sperm that naturally bind to an egg's outer shell leads to better IVF outcomes than having an embryologist manually choose sperm. Researchers compared embryo development and pregnancy rates between these two methods in 29 couples undergoing the…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: IVI America • Aim: Disease control
Last updated Apr 01, 2026 21:41 UTC
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Can shedding pounds before IVF boost your chances of a baby?
Disease control CompletedThis study tested whether losing weight before starting IVF treatment helps overweight women have a baby. Researchers split 158 women into two groups: one followed a 3-month diet and exercise plan before IVF, while the other received standard care. The goal was to see if the weig…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New IVF technique aims to boost embryo success
Disease control CompletedThis study tested a new method for preparing sperm samples for IVF/ICSI fertility treatments. Researchers compared this new approach to standard procedures to see if it could improve embryo development. The study involved 41 couples undergoing fertility treatment, measuring how m…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: Fecundis S.A. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New IVF approach aims for more babies, fewer hormone side effects
Disease control CompletedThis study tested a new fertility treatment method for women undergoing IVF. The goal was to see if creating a more natural hormone environment during egg stimulation could lead to better pregnancy and live birth rates compared to the standard method. The study involved 129 women…
Matched conditions: INFERTILITY
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Robots step into the IVF lab: study tests automated embryo creation
Disease control CompletedThis study tested whether robots and automation could handle key steps in the IVF process, from preparing sperm and eggs to fertilizing embryos and freezing them. Researchers compared outcomes from automated procedures against the standard manual methods performed by embryologist…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: Conceivable Life Sciences • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New IVF treatment approach aims to boost live birth rates
Disease control CompletedThis study tested whether adding a daily hormone injection (HMG) for two weeks after egg retrieval could improve pregnancy outcomes for women undergoing IVF. The trial involved 600 women aged 20-40 who were receiving standard IVF treatment. Researchers compared live birth rates b…
Matched conditions: INFERTILITY
Phase: PHASE4 • Sponsor: Cairo University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New dosing strategy tested to boost ovulation in women with PCOS
Disease control CompletedThis study tested if starting with a low dose of the fertility drug letrozole and gradually increasing it (step-up) works better than a standard fixed dose for helping women with PCOS ovulate. It involved 70 women with PCOS-related infertility over three treatment cycles. The goa…
Matched conditions: INFERTILITY
Phase: PHASE3 • Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Does the egg freezing liquid matter for getting pregnant?
Disease control CompletedThis study looked back at 111 fertility treatments using donated eggs to see if the type of solution used to freeze the eggs affects pregnancy success. Researchers compared a solution made specifically for eggs to a more general-purpose one. The goal was to find out if one soluti…
Matched conditions: INFERTILITY
Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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IVF rescue mission: second trigger saves cycles after empty retrieval
Disease control CompletedThis study looked at whether giving a second ovulation trigger medication could successfully collect eggs from women whose first IVF egg retrieval attempt failed to get any eggs. It included 87 women who had this specific problem. Researchers compared different trigger medication…
Matched conditions: INFERTILITY
Sponsor: Clinique Ovo • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Two-Hormone IVF trigger shows promise for better eggs
Disease control CompletedThis study tested if adding a second hormone (FSH) to the standard one-hormone (hCG) injection given before egg retrieval could improve outcomes for people undergoing IVF. Researchers wanted to see if this two-hormone approach, which more closely mimics a natural menstrual cycle,…
Matched conditions: INFERTILITY
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New hope for IVF? treatment aims to boost fertilization for tough cases
Disease control CompletedThis study tested a lab treatment called GM508 CultActive for people undergoing IVF who had poor fertilization or embryo development in past cycles. It aimed to see if treating eggs with this solution could improve the chance of successful fertilization and lead to higher-quality…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: Chang Gung Memorial Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Could a simple test boost IVF success for women with immune issues?
Disease control CompletedThis study looked back at medical records to see if testing women's sensitivity to a common immune medication (glucocorticoids) before embryo transfer affected their chances of having a baby. It included 148 women under 40 with infertility linked to an overactive immune system in…
Matched conditions: INFERTILITY
Sponsor: Hopital Pierre Rouques - Les Bluets • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New IVF drug protocol aims for better embryos, fewer side effects
Disease control CompletedThis completed study looked back at 118 women undergoing IVF treatment to see if using a higher dose of a specific fertility medication (follitropin delta) alongside another hormone could improve embryo quality. The research aimed to build on previous findings that personalized d…
Matched conditions: INFERTILITY
Sponsor: Clinique Ovo • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Chip vs. spin: new IVF method aims for healthier embryos
Disease control CompletedThis study tested a new, gentler method for selecting sperm for IVF. Couples with a history of poor embryo quality were randomly assigned to have sperm prepared either with the standard lab method (centrifugation) or a new microfluidic chip. The chip aims to isolate healthier, mo…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New IVF test aims to boost pregnancy success without touching the embryo
Diagnosis CompletedThis study tested whether a new, non-invasive test could help doctors choose the best embryos during IVF treatment. Researchers compared pregnancy and birth rates between two groups: one where embryos were selected using the new test plus standard visual grading, and another usin…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: Peking University Third Hospital • Aim: Diagnosis
Last updated Apr 01, 2026 21:41 UTC
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New therapy aims to ease the mental burden of infertility
Symptom relief CompletedThis small study tested whether a specific type of talk therapy could help people struggling with the emotional distress of infertility. Nine participants received 12 therapy sessions focused on managing difficult thoughts and feelings. The main goal was to see if patients found …
Matched conditions: INFERTILITY
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Can a sleep hormone boost your IVF success?
Symptom relief CompletedThis study tested whether taking melatonin supplements could improve outcomes for women undergoing in vitro fertilization (IVF). Researchers gave 80 infertile women either melatonin or a placebo during their IVF treatment cycle. They measured hormone levels, egg quality, embryo d…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Special nursing care eases the emotional burden of infertility
Symptom relief CompletedThis study tested whether a special nursing care program could help women feel less stressed and more supported while undergoing infertility treatment. Researchers in Egypt worked with 80 women experiencing secondary infertility, splitting them into two groups: one received the n…
Matched conditions: INFERTILITY
Phase: NA • Sponsor: Fayoum University • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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New approach to ease IVF pain shows promise
Symptom relief CompletedThis study tested whether a new pain management protocol could better help women undergoing in vitro fertilization (IVF). Researchers compared 206 patients using the new approach to data from previous patients to see if it reduced pain during treatment. The study focused particul…
Matched conditions: INFERTILITY
Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Mar 18, 2026 14:41 UTC
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French hospital tests which Baby-Making machine works best
Knowledge-focused CompletedThis study compared two advanced embryo incubators used during IVF treatment to see which one helps embryos implant better. Researchers followed 388 women undergoing IVF with a specific sperm injection technique, randomly assigning them to one of the two incubator systems. The ma…
Matched conditions: INFERTILITY
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Five-Year checkup: are IVF and IVM kids developing the same?
Knowledge-focused CompletedThis study followed 214 children for five years to see if those born using a newer fertility method (CAPA-IVM) develop similarly to those born using the standard method (conventional IVF). Researchers checked the children's physical growth, behavior, and skills like communication…
Matched conditions: INFERTILITY
Sponsor: Mỹ Đức Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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The hidden toll: how IVF impacts working Women's well-being
Knowledge-focused CompletedThis study aimed to understand how in vitro fertilization (IVF) treatment affects the quality of life of women who are also working. Researchers followed 200 employed women in France through their first IVF attempt, using questionnaires to measure their stress, mood, and work-lif…
Matched conditions: INFERTILITY
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Could your diet be the key to getting pregnant?
Knowledge-focused CompletedThis study aimed to understand how diet and lifestyle affect a couple's ability to conceive. Researchers compared 400 fertile and infertile couples, looking at their nutrition, body measurements, blood tests, and lifestyle habits. The goal was to find connections between what peo…
Matched conditions: INFERTILITY
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists track fertility hormones in healthy women
Knowledge-focused CompletedThis study aimed to understand how the body absorbs and processes two specific fertility hormones (FSH and hCG) after a single injection. It involved 29 healthy, premenopausal women who were taking birth control pills. The main goal was to measure hormone levels in the blood over…
Matched conditions: INFERTILITY
Phase: PHASE1 • Sponsor: IBSA Institut Biochimique SA • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists track hormone journey in women to improve fertility treatments
Knowledge-focused CompletedThis study aimed to understand how the body absorbs and processes two specific fertility hormones (FSH and hCG) when given as daily injections under the skin. It involved 28 healthy women of childbearing age who were already using birth control pills. The main goal was to measure…
Matched conditions: INFERTILITY
Phase: PHASE1 • Sponsor: IBSA Institut Biochimique SA • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Could a simple blood test predict IUI success?
Knowledge-focused CompletedThis study aimed to see if a woman's progesterone level on the day of a fertility treatment called intrauterine insemination (IUI) is linked to her chances of getting pregnant. Researchers observed 158 women undergoing IUI to collect this data. The goal was to gather knowledge th…
Matched conditions: INFERTILITY
Sponsor: Centre Hospitalier Intercommunal Creteil • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Scientists search egg cells for secret code to better IVF babies
Knowledge-focused CompletedThis study aimed to find genetic markers in the cells surrounding a woman's eggs that could help predict which embryos are most likely to develop well and lead to a successful pregnancy. Researchers observed 137 women undergoing IVF treatment, collecting cells from their eggs to …
Matched conditions: INFERTILITY
Sponsor: Fertiga, Belgium • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC
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Scientists probe mystery of missing puberty hormones
Knowledge-focused CompletedThis study aimed to understand a rare condition where the body doesn't produce enough of a key hormone (GnRH) needed to start puberty and support fertility. Researchers studied 111 teenagers and adults with this condition to map their hormone patterns and look for other related h…
Matched conditions: INFERTILITY
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC