Could a simple swab replace painful uterine biopsies?

NCT ID NCT06920797

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether less invasive methods—a vaginal swab or a fluid sample from the uterus—can accurately measure the microbiome (bacteria) in the womb, compared to the standard endometrial biopsy. Fifty-seven women provided samples at two time points. The goal is to find a gentler, safer way to study the uterine environment, which may help understand fertility issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to simpler, less painful ways to analyze the uterine microbiome, potentially improving fertility assessments.
What could go wrong
This is a small, early pilot study focused on method comparison, not treatment. The techniques may not prove reliable enough for clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vida Recoletas Sevilla

    Seville, Seville, 41092, Spain

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