COVID-19's hidden presence: could the virus lurk in sperm?

NCT ID NCT04487639

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study looks at whether the virus that causes COVID-19 can be found in the semen of men with cancer who are storing sperm before treatment. Researchers will test both the fluid and the sperm cells for the virus and compare results with nasal swabs and blood tests. The goal is to understand if the virus can be present in sperm, which could affect fertility preservation safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Diagnostic tests for SARS-CoV-2 (nasopharyngeal swab, semen analysis, and serology)
What this could lead to
If the virus is found in semen, it could inform safety protocols for fertility preservation and raise awareness about potential sexual transmission.
What could go wrong
This is an observational study, so it won't test treatments. The presence of the virus in semen may not be confirmed, and findings may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-Hôpitaux de Paris - Hôpital Antoine Béclére - Service de Biologie de la reproduction et AMP DPI CECOS

    Clamart, France, 92140, France

  • AP-Hôpitaux de Paris - Hôpital Cochin - Service d'Histologie-Embryologie-Biologie de la reproduction

    Paris, France, 75014, France

  • AP-Hôpitaux de Paris - Hôpital Jean Verdier - Service de Biologie de la reproduction

    Bondy, France, 93140, France

  • AP-Hôpitaux de Paris - Hôpital Tenon - Service de Biologie de la reproduction - CECOS

    Paris, France, 75000, France

  • CHU de Clermont-Ferrand

    Clermont-Ferrand, France, 63000, France

  • CHU de Clermont-Ferrand - Laboratoire de Virologie

    Clermont-Ferrand, France, 63000, France

  • CHU de Dijon - Laboratoire de Biologie de la Reproduction-CECOS

    Dijon, France, France

  • CHU de Grenoble - Laboratoire d'Aide à la Procréation CECOS

    Grenoble, France, 38000, France

  • CHU de Nancy - Laboratoire de biologie de la reproduction - CECOS

    Nancy, France, 54000, France

  • CHU de Reims - Service de Biologie de la Reproduction - CECOS Champagne-Ardenne de Reims

    Reims, 51000, France

  • CHU de Rouen Normandie - Service Biologie de la Reproduction-CECOS

    Rouen, France, 76000, France

  • CHU de Strasbourg - Service de Biologie de la reproduction

    Strasbourg, France, 67000, France

  • CHU de Toulouse - CECOS Midi-Pyrénées

    Toulouse, France, 31000, France

  • Centre Hospitalier intercommunal (CHI) de Poissy Saint Germain en Laye

    Poissy, France, 78300, France

  • Hospices Civils de Lyon - Service AMP-CECOS

    Lyon, France, 69000, France

  • Hôpital de la Conception - AP-Hôpitaux de Marseille - Service AMP-CECOS

    Marseille, France, 13000, France

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