FERTILITY

This study compares three surgical treatments for endometriomas (ovarian cysts from endometriosis) in 332 women aged 18-43 who want to become pregnant. Participants are randomly assigned to cystectomy, plasma vaporization, or sclerotherapy. The main goal is to see which approach …

This study aims to improve fertility-sparing treatment for young women (ages 18-45) with endometrial cancer by tailoring therapy to the tumor's genetic profile. Participants will receive either hormone therapy (progestins) or a combination with an immunotherapy drug (sintilimab),…

This study is testing a new device called Plan A that blocks sperm from passing through the vas deferens, similar to a vasectomy, but designed to be reversed later. Forty healthy men aged 25 to 65 will receive the device and be monitored for safety and effectiveness. The goal is …

This study compares a new semi-automatic machine (GAVI®) to the standard manual method for freezing donor eggs. Researchers want to see if the machine can freeze eggs just as well, with similar survival rates after thawing. The trial involves 50 egg donors and will also look at f…

This study follows 650 women with endometriosis who want to have children after diagnosis. Researchers compare pregnancy rates and the need for fertility treatments between those who had surgery and those who took medication. The goal is to understand which approach leads to bett…

This study looks at different ways to track ovulation and the luteal phase using the Premom app. Thirty women will record cervical mucus, urine test results, and body temperature over three cycles. The goal is to see which combination of signs gives the most accurate picture of w…

This study follows 270 women under 40 who have had melanoma removed and are now taking adjuvant therapies like dabrafenib, trametinib, pembrolizumab, or nivolumab. Researchers will measure ovarian reserve using a blood test before and after treatment to see how these drugs affect…