New study to reveal if modern melanoma drugs harm fertility
NCT ID NCT07092670
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study follows 270 women under 40 who have had melanoma removed and are now taking adjuvant therapies like dabrafenib, trametinib, pembrolizumab, or nivolumab. Researchers will measure ovarian reserve using a blood test before and after treatment to see how these drugs affect fertility. The goal is to help doctors and patients decide whether to pursue fertility preservation before starting treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors better understand which melanoma treatments affect fertility and guide women on whether to consider egg freezing before starting therapy.
What could go wrong
This is an observational study, not a treatment trial. It will not test new drugs or change outcomes. Results may take years and may not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda Ospedaliera Santa Maria della Misericordia - Unità di Oncologia Medica.
RECRUITINGPerugia, 06132, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Ospedaliero-Universitaria, Modena
NOT_YET_RECRUITINGModena, 41125, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fondazione IRCCS Istituto Nazionale dei Tumori
NOT_YET_RECRUITINGMilan, 20861, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
NOT_YET_RECRUITINGRoma, 00168, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IOV Istituto Oncologico Veneto
NOT_YET_RECRUITINGPadova, 35128, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Ospedale Policlinico San Martino, Oncologia Medica 2
NOT_YET_RECRUITINGGenova, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Istituto Nazionale Tumori "Fondazione Pascale"
NOT_YET_RECRUITINGNaples, 80016, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ospedale Oncologico "Giovanni Paolo II"
NOT_YET_RECRUITINGBari, 70122, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Università degli Studi di Siena - U.O.C. Immunoterapia Oncologica Azienda Ospedaliera Universitaria Senese
NOT_YET_RECRUITINGSiena, 53035, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Università di Torino - Clinica Dermatologica
NOT_YET_RECRUITINGTorino, 10126, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••