Could a sleep hormone boost IVF success?
NCT ID NCT07343947
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking melatonin, a natural antioxidant, can improve egg quality and pregnancy rates in women undergoing IVF. Eighty infertile women received either melatonin or a placebo. Researchers measured melatonin levels in ovarian fluid and tracked egg maturation, embryo development, and pregnancy. The goal is to see if this simple supplement can help women struggling with infertility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
melatonin
What this could lead to
If it works, this could point toward a simple, low-cost supplement to improve IVF success rates.
What could go wrong
This is a small, completed trial with 80 participants. Melatonin is not a standard fertility treatment, and results may not apply to all women or lead to higher pregnancy rates.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Univertity of Sao Paulo, Clinics Hospital
São Paulo, São Paulo, Brazil