New sperm selection method tested for IVF success

NCT ID NCT05859152

Completed Knowledge-focused Sponsor: IVI America Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new way to select sperm for IVF. Instead of an embryologist picking the best-looking sperm, they used sperm that naturally attached to the outer layer of an immature egg. The goal was to see if this method leads to more embryos developing into blastocysts. The study involved 29 couples undergoing their first IVF cycle.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Zona Pellucida-Bound Sperm Selection for ICSI
What this could lead to: If this method works, it could improve embryo quality and success rates for IVF patients.
What could go wrong: This is a small, early-stage study with only 29 participants. The new method may not be better than the standard approach, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFERTILITY

Contacts and locations

Locations

Reproductive Medicine Associates of Northern California

San Francisco, California, 94105, United States

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