Could a Two-Hormone trigger boost IVF success?
NCT ID NCT00854373
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looked at whether giving an extra hormone (FSH) along with the usual hCG trigger before egg retrieval in IVF can improve egg quality and pregnancy rates. 232 women undergoing IVF took part. The goal was to see if this approach, which mimics a natural menstrual cycle, leads to better fertilization and more pregnancies.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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232 people
The number who actually took part.
- Started
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Jun 2007
- Finished
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Apr 2010
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients undergoing in vitro fertilization Exclusion Criteria: * risk of ovarian hyperstimulation syndrome
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UCSF- Mission Bay
San Francisco, California, 94158, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a lighter touch in IVF yield healthier embryos for women over 35?
- Can a simpler fertility drug dose match the standard for IUI success?
- A Hormone-Free IVF path? Lab-Matured eggs put to the test
- Can a fertility drug's safety be tracked in real-world use?
- Can a suppository or a local block take the pain out of fertility testing?
- Can a lab technique mature eggs more gently for IVF?