New chip could pick healthier sperm for IVF

NCT ID NCT03085433

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a microfluidic chip that gently separates healthy, motile sperm from semen without harsh chemicals. Researchers compared it to the standard spinning method in 393 couples undergoing IVF for unexplained infertility. The goal was to see if the chip leads to higher-quality embryos on day 3 of development.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Microfluidic sperm sorting device

What this could lead to

If successful, this device could become a standard, gentler way to select sperm for IVF, potentially improving embryo quality and pregnancy chances.

What could go wrong

This is a completed trial, but the improvement in embryo quality may not translate into higher live birth rates. The device may not work for all types of male infertility.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infertility disorder male infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California San Francisco

    San Francisco, California, 94158, United States