INFERTILITY

This study is testing whether adding a specific Chinese herbal formula to standard ovulation therapy helps more women with diminished ovarian reserve get pregnant naturally. It will compare pregnancy rates between women receiving the combined treatment and those receiving standar…

This study is testing the safety of a new sperm preparation method for in vitro fertilization (IVF). It will compare the new method to standard procedures to see if it leads to healthier embryos and better pregnancy rates. The trial will involve about 200 couples undergoing IVF t…

This study compares two medications to see which works better at helping men with infertility produce more sperm. Adult men aged 19-50 with low or no sperm counts will be randomly assigned to take either a pill (isotretinoin) or receive hormone injections (hCG) for three months. …

This study is testing a new AI-powered tool called IntelliWell. It aims to find rare, usable sperm in testicular tissue samples from men with a severe form of infertility where no sperm is found in semen. If the AI successfully finds sperm that standard lab methods missed, those …

This study aims to test whether platelet-rich plasma (PRP) made from donated blood can improve sperm quality in men with infertility. Researchers will first develop a standard method to prepare the PRP, then test if adding it to sperm samples increases their movement and health. …

This study is testing whether a game-like mobile training program can help women feel more confident and adopt healthier habits while they go through stressful fertility treatments like IVF. Researchers will compare the app-based training to receiving just a booklet or standard c…

This study aims to understand how different microbes (like viruses and bacteria) are shared between partners and if they affect infertility and pregnancy. It will follow 200 couples undergoing fertility treatments for two years, collecting samples from their mouths and genitals. …

This study aims to understand what happens to couples after they go through a specialized IVF process with genetic testing (PGT) that does not result in a baby. Researchers will follow 900 couples from a Paris clinic to learn about their future family-building choices, such as tr…

This study aims to understand why pregnancies from frozen embryo transfers sometimes have more complications, like high blood pressure, than fresh transfers or natural pregnancies. Researchers will measure levels of a pregnancy hormone called relaxin in the blood of 60 women who …

This study aims to understand if infertility or IVF treatments are linked to a higher risk of future heart and metabolic problems in women. Researchers will recruit 120 women in Manchester, some planning pregnancy and some who have already had a baby, to measure their heart and b…

This study aims to find out if having a tattoo affects pregnancy success for women undergoing IVF fertility treatment. Researchers will follow about 328 women aged 21-40 who are having embryo transfers, comparing pregnancy outcomes between those with and without tattoos. The stud…

This study aims to test how well a new artificial intelligence (AI) software tool, called MAGENTA BLAST, can help embryologists during IVF treatment. The tool analyzes images of embryos on Day 3 to predict which ones are most likely to develop into a healthy blastocyst by Day 5. …

This study aims to understand how the uterus's natural, wave-like contractions affect pregnancy success during frozen embryo transfers. Researchers will observe women undergoing two common fertility treatment protocols to see if specific contraction patterns are linked to higher …

This study aims to use artificial intelligence (AI) to improve the success of in vitro fertilization (IVF). Researchers will analyze video recordings of developing embryos and patient health data from 1,500 couples to find patterns that predict which embryo is most likely to impl…

This study aims to understand if having deep endometriosis in the bowel increases a person's risk of developing colorectal cancer. Researchers will enroll 30 female patients who are already scheduled for surgery to treat their bowel endometriosis. They will compare the genetic ac…