INFERTILITY

This study compares two methods to trigger final egg maturation in women with poor ovarian response (POSEIDON groups 3 and 4) undergoing IVF. One group receives the standard HCG trigger, while the other gets a double trigger combining GnRH agonist and HCG. The goal is to see if t…

This study tests a new way to prepare sperm for in vitro fertilization (IVF) to see if it is safe and helps create healthier embryos. About 202 couples undergoing IVF will take part, with the new method compared to the standard one. The main goal is to see if embryos have the rig…

This study tests whether adding a traditional Chinese herbal formula to standard ovulation induction therapy improves pregnancy rates in women aged 22-39 with diminished ovarian reserve (low egg supply) and infertility. About 320 participants will receive either the combined trea…

This study tests whether giving three doses of a hormone trigger (GnRH agonist) instead of the usual single dose before egg retrieval improves egg quality and pregnancy rates in women who produce many eggs during IVF. About 190 participants will be randomly assigned to one of the…

This study looks at whether taking progesterone after intrauterine insemination (IUI) can increase the chance of pregnancy in women who used letrozole for ovarian stimulation. About 690 women at four Danish fertility clinics will be randomly assigned to receive either vaginal pro…

This study looks at a fertility drug called corifollitropin alfa in women aged 36 to 40 who are having in vitro fertilization (IVF). The goal is to see if the drug is safe and helps with pregnancy rates. About 200 women will take part and be followed for one year.

This study explores whether a special blood product called pure platelet-rich plasma (P-PRP) can improve sperm movement when mixed with semen in a lab. Researchers will first standardize how to make P-PRP, then test it on sperm samples from 248 volunteers. The goal is to see if P…

This study tests whether a gamified healthy lifestyle training program helps women undergoing fertility treatments like IVF feel more confident and adopt healthier habits. About 105 women will be split into three groups: one gets the game-like program plus a booklet, another gets…

This study looks at how different germs (like bacteria and viruses) spread between partners who are having trouble getting pregnant. Researchers will follow 200 couples for two years, collecting samples from the mouth and genitals every six months. The goal is to learn more about…

This study looks at whether tiny plastic particles in the body are linked to fertility problems. Researchers will measure microplastics in semen, fluid from eggs, and other samples from 1,000 men and women. The goal is to understand how these particles might affect pregnancy rate…

This study looks at 1,500 couples undergoing IVF to see if a computer can learn to predict which embryos will successfully implant in the womb. Researchers will use time-lapse videos of embryo development and patient health data to train a machine learning algorithm. The goal is …

This study tests a new ultra-rapid method for freezing embryos (blastocysts) in egg donation cycles. Researchers want to see if this faster freezing technique is as safe and effective as the standard method. The study will involve 80 women receiving donor eggs and will compare em…

This study looks at whether special lab-grown cells (made from stem cells) can help immature eggs from IVF patients mature in a dish. About 100 women will donate eggs that are not yet ready, and each woman's eggs will be split into two groups: one grown the usual way and one grow…

This study explores whether having a tattoo influences pregnancy success in women undergoing IVF. Researchers will compare pregnancy rates, including live births and miscarriages, between women with and without tattoos. The goal is to understand if tattoo-related inflammation aff…

This study looks at whether infertility or IVF treatments are linked to heart and blood vessel problems in women. Researchers will recruit 120 women planning pregnancy (with or without IVF) and compare their heart and metabolic health. The goal is to understand any connections an…

This study looks at whether women with deep endometriosis affecting the bowel have a higher chance of developing colorectal cancer. Researchers will compare gene activity in healthy and endometriosis-affected bowel tissue from 30 women having surgery. The goal is to improve risk …

This study looks at the reproductive health experiences of over 1,100 female Canadian Armed Forces members and veterans. It covers contraception, pregnancy, infertility, and pelvic floor issues, plus access to care and career effects. The goal is to gather information through sur…

This study looks at a hormone called relaxin in women who become pregnant after embryo transfer. Researchers want to see if relaxin levels differ between fresh and frozen embryo transfers, which may help explain why frozen transfers have higher risks of problems like preeclampsia…