Could extra doses of a hormone boost IVF success for high responders?
NCT ID NCT07569315
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares giving three doses of a GnRH agonist (triptorelin) versus the usual single dose to trigger ovulation in women who produce many eggs during IVF. The goal is to see if multiple doses lead to more mature eggs and higher pregnancy rates. The trial plans to enroll 190 women classified as hyper-responders.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Triptorelin (GnRH agonist)
- What this could lead to
- If successful, this could improve the number of mature eggs retrieved during IVF for women who over-respond to stimulation, potentially increasing pregnancy chances.
- What could go wrong
- This is a small Phase 2 trial, so results may not apply broadly. The intervention is a variation of an existing drug, so the benefit over standard care may be modest or absent.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INFERTILITY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bedaya Hospital
Giza, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can 'Abnormal' embryos still lead to healthy pregnancies? a new registry investigates
- Building a biological treasure trove to decode Women's health mysteries
- Can a sperm 'Quality Check' boost IVF success?
- Foam ultrasound for fertility checks: will women find it comfortable?
- A Hormone's hidden power: could progesterone be the key to unexplained infertility?
- A questionnaire to empower fertility patients — a pilot study puts it to the test