Microplastics in your body linked to fertility troubles?
NCT ID NCT07562958
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will measure microplastics in semen, follicular fluid, and other samples from 1000 men and women seeking fertility treatment. Researchers will check if higher microplastic levels are linked to lower pregnancy rates and poorer egg or sperm quality. The goal is to better understand how environmental pollutants may harm reproductive health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could provide strong evidence linking microplastic exposure to fertility problems, guiding future public health advice or interventions.
- What could go wrong
- This is an observational study, not a treatment trial. It can show links but not prove cause and effect. Results may be complex and not lead to immediate changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2027
An estimate. Start dates often move.
- Expected to finish
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Oct 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults of reproductive age
- Ages
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18 to 55 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men: 18-55 years and women: 18-45 years (premenopausal). * Residence: ≥ 2 years in the participating region. * Ability to give informed consent and complete questionnaires (diet, lifestyle, occupational exposure). * Willingness to provide required samples: semen, serum, stool for men and for women serum, stool, follicular fluid and endometrial sample. * Availability for study visits and compliance with pre-analytical rules: Abstinence 2-7 days before semen collection and timed sampling in women (e.g., follicular phase or per protocol). * For patient cohort: diagnosed reproductive disorder per site SOPs (e.g., male factor infertility, endometriosis, diminished ovarian reserve). * For control cohort: no known infertility diagnosis; trying to conceive or healthy volunteers. * Necessary for all participants will be possess the ability to understand the information contained in the "informed consent" document. Exclusion Criteria: * Pregnancy or lactation. * Acute febrile illness or active urogenital/reproductive tract infection in the last 4 weeks. * Systemic therapies likely to confound biomarkers within prespecified windows: chemotherapy/radiotherapy (past 12 months), high-dose corticosteroids/immunosuppressants (past 3 months), hormonal stimulation outside scheduled ART cycles per protocol. * Substance abuse (investigator judgment) impeding consent/compliance.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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