Ancient herbs meet modern medicine in new fertility trial for women with low egg reserve
NCT ID NCT07296614
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 3 trial will test whether adding a traditional Chinese herbal formula to the standard fertility drug letrozole can improve natural pregnancy rates in women aged 22–39 with diminished ovarian reserve (low egg supply). The study plans to enroll 320 women who will receive either the combined treatment or a placebo plus letrozole. The main goal is to see if more women achieve a confirmed pregnancy within the study period.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Letrozole and Xiehe DOR Kidney-Tonifying Universal Formula (Chinese herbal granules)
- What this could lead to
- If successful, this combination therapy could offer a new, non-invasive option to help women with diminished ovarian reserve conceive naturally without IVF.
- What could go wrong
- This is a Phase 3 trial, but it has not yet started recruiting. The herbal formula is specific to Chinese medicine diagnosis, so results may not apply to all women. There is also a risk the placebo group performs similarly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIMINISHED OVARIAN RESERVE (DOR) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Peking union medical college hospital
Beijing, Beijing Municipality, 100730, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can 'Abnormal' embryos still lead to healthy pregnancies? a new registry investigates
- Building a biological treasure trove to decode Women's health mysteries
- Can a sperm 'Quality Check' boost IVF success?
- Ancient herbal formula put to the test for boosting egg maturity
- Foam ultrasound for fertility checks: will women find it comfortable?
- A Hormone's hidden power: could progesterone be the key to unexplained infertility?