Ancient herbs meet modern medicine in new fertility trial for women with low egg reserve

NCT ID NCT07296614

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial will test whether adding a traditional Chinese herbal formula to the standard fertility drug letrozole can improve natural pregnancy rates in women aged 22–39 with diminished ovarian reserve (low egg supply). The study plans to enroll 320 women who will receive either the combined treatment or a placebo plus letrozole. The main goal is to see if more women achieve a confirmed pregnancy within the study period.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Letrozole and Xiehe DOR Kidney-Tonifying Universal Formula (Chinese herbal granules)

What this could lead to

If successful, this combination therapy could offer a new, non-invasive option to help women with diminished ovarian reserve conceive naturally without IVF.

What could go wrong

This is a Phase 3 trial, but it has not yet started recruiting. The herbal formula is specific to Chinese medicine diagnosis, so results may not apply to all women. There is also a risk the placebo group performs similarly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infertility disorder ovarian dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking union medical college hospital

    Beijing, Beijing Municipality, 100730, China