GINGIVITIS
Clinical trials for GINGIVITIS explained in plain language.
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New toothpaste fights gum disease in just 4 weeks
Disease control CompletedThis study tested a special toothpaste with stannous fluoride, zinc, and alumina to see if it improves gum health and reduces plaque better than regular fluoride toothpaste. 175 adults with mild to moderate gingivitis used the toothpaste for 4 weeks. The main goal was to measure …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 17, 2026 02:37 UTC
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Mouthwash showdown: which rinse best fights gum disease?
Disease control CompletedThis study tested two mouthwashes in 72 adults with gum disease (gingivitis or periodontitis) to see which better controls inflammation and bacteria. Participants used either a standard chlorhexidine rinse or a combination rinse with chlorhexidine and cetylpyridinium chloride for…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Siena • Aim: Disease control
Last updated May 17, 2026 02:35 UTC
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Ancient herbal mouthwash takes on modern dental standard
Disease control CompletedThis study tested whether a mouthwash made from Triphala, an Ayurvedic herbal blend, works as well as the standard chlorhexidine mouthwash for reducing plaque and gum inflammation (gingivitis). 220 adults with mild to moderate gingivitis used one of the two mouthwashes. The goal …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Bangladesh Medical University • Aim: Disease control
Last updated May 17, 2026 02:34 UTC
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New mouthwash fights plaque and gum trouble on implants
Disease control CompletedThis study tested a new mouthwash containing CPC, hyaluronic acid, and zinc lactate against a standard fluoride mouthwash. 80 adults with at least two dental implants used the rinse for 6 months to see if it reduced plaque and prevented gum inflammation (gingivitis). The goal was…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 17, 2026 02:34 UTC
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Toothpaste plus mouthwash: a better brush for plaque and gums?
Disease control CompletedThis study compared two brushing regimens: one using a special toothpaste with mouthwash, and the other using regular fluoride toothpaste. Over 12 weeks, 90 adults aged 18-70 with mild gum problems and plaque were monitored. The goal was to see which routine better reduced plaque…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 17, 2026 02:27 UTC
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Beer ingredient toothpaste fights gum disease in new study
Disease control CompletedThis study tested two new toothpastes containing hops extract to see if they reduce gingivitis (gum inflammation) better than a standard fluoride toothpaste. 120 adults used the toothpaste for 12 weeks, and researchers measured bleeding gums and inflammation. The goal was to find…
Matched conditions: GINGIVITIS
Phase: PHASE2 • Sponsor: Procter and Gamble • Aim: Disease control
Last updated May 17, 2026 02:27 UTC
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Chewing gum that may help your gums and heart?
Disease control CompletedThis study tested whether a chewing gum containing dietary nitrate (like in leafy greens and beets) could improve gum health and heart health in adults with mild gum disease. Thirty participants were randomly assigned to use either the nitrate gum or a placebo gum for three weeks…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated May 17, 2026 02:26 UTC
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Gum health boost? black seed toothpaste tested on soldiers
Disease control CompletedThis study looked at whether a toothpaste made from black seed (Nigella sativa) can lower signs of gum inflammation in Indonesian soldiers with gingivitis. One hundred soldiers used the toothpaste, and researchers measured certain markers in their saliva to see if inflammation de…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Universitas Airlangga • Aim: Disease control
Last updated May 17, 2026 02:25 UTC
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Toothpaste and mouthwash combo takes on gum disease in new study
Disease control CompletedThis study tested whether using a special toothpaste with stannous fluoride plus a mouthwash with cetylpyridinium chloride works better than regular fluoride toothpaste for reducing plaque and gum inflammation. 82 adults with mild to moderate gum disease brushed at home and were …
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New toothpaste and brush combo takes on plaque and gingivitis in 3-Month showdown
Disease control CompletedThis study compared a stannous fluoride toothpaste paired with a new toothbrush to a standard Colgate toothpaste and regular toothbrush for reducing plaque and gingivitis. 95 adults with mild to moderate gum inflammation and plaque buildup brushed twice daily for 3 months. Resear…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New toothpaste aims to fight plaque and gum disease
Disease control CompletedThis study tested whether a new Colgate toothpaste with dual zinc can better control plaque and gingivitis (early gum disease) compared to a standard cavity-protection toothpaste. 86 adults with mild to moderate plaque and gum inflammation used one of the two toothpastes for thre…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New toothbrush could revolutionize your gum health!
Disease control CompletedThis study tested whether a full-mouth electronic toothbrush (FMET) reduces gum inflammation (gingivitis) and plaque better than a regular electronic toothbrush. 94 adults with mild to moderate gingivitis used one of three brushing methods. Researchers measured gum health and pla…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Minnesota • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Baking soda toothpaste takes on gum disease in new study
Disease control CompletedThis study looked at whether a toothpaste with sodium bicarbonate (baking soda) can change the bacteria in your mouth better than regular fluoride toothpaste. 74 adults with mild gum disease (gingivitis) used the toothpaste for 12 weeks. Researchers checked plaque samples to see …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Mouthwash breakthrough? new study shows promise for gum health
Disease control CompletedThis study tested whether a mouthwash containing cetylpyridinium chloride (CPC) can improve gum health and reduce plaque buildup when used alongside regular brushing. 136 adults with mild to moderate gingivitis used the CPC mouthwash or just brushed with fluoride toothpaste for 1…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Floss vs. mouthwash: which wins the battle against plaque?
Disease control CompletedThis study tested how well floss and three different mouthwashes (one with essential oils and alcohol, one with essential oils but no alcohol, and one with CPC+Zn and no alcohol) reduce plaque and gum inflammation. 228 adults with mild to moderate gum disease took part. The goal …
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Mouthwash and toothpaste duo fights gum bleeding in new study
Disease control CompletedThis study looked at whether using a stannous fluoride toothpaste together with a cetylpyridinium chloride mouthwash can improve gum health and reduce plaque better than using regular fluoride toothpaste alone. 199 adults with gum inflammation (gingivitis) took part. The main goa…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 11, 2026 20:54 UTC
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Toothbrush showdown: can a simple brush beat gingivitis?
Disease control CompletedThis study tested two different manual toothbrushes to see how well they reduce plaque and gum inflammation (gingivitis). 84 adults brushed at home with their assigned toothbrush and were checked by a dentist after 1, 3, and 6 weeks. The goal was to find out which brush works bet…
Matched conditions: GINGIVITIS
Phase: PHASE2 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 07, 2026 18:41 UTC
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Battery toothbrush beats manual in gum health showdown
Disease control CompletedThis study compared a battery toothbrush to a manual toothbrush for reducing plaque and gingivitis (gum inflammation) in 130 adults over 12 weeks. Participants had mild to moderate gum disease and plaque at the start. Dentists measured gum health and plaque levels using standard …
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 06, 2026 16:03 UTC
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Smokers who switch to vapes or Heat-Not-Burn may see healthier gums
Disease control CompletedThis study looked at whether smokers who switch to combustion-free nicotine delivery systems (like e-cigarettes or heated tobacco) see improvements in gum health and tooth appearance compared to those who keep smoking or never smoked. About 460 healthy adults took part, and resea…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Eclat Srl. • Aim: Disease control
Last updated May 04, 2026 16:23 UTC
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Herbal mouthwash challenges standard gum treatment in new study
Disease control CompletedThis study tested whether a new herbal mouthwash and gel could reduce plaque and gum inflammation as effectively as the standard chlorhexidine treatment, which can cause side effects like tooth staining and taste changes. Researchers compared the two products in 34 healthy adults…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Stony Brook University • Aim: Disease control
Last updated Apr 21, 2026 12:44 UTC
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Power brush and rinse show promise for healthier gums in 6-Week study
Symptom relief CompletedThis study tested whether using a power toothbrush followed by a mouth rinse twice daily for 6 weeks reduces gum bleeding and inflammation better than brushing with a manual toothbrush alone. 69 adults with gingivitis participated. Researchers measured gum health at the start and…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Procter and Gamble • Aim: Symptom relief
Last updated May 17, 2026 02:25 UTC
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New toothpaste fights gum bleeding in 12-week trial
Symptom relief CompletedThis study tested an experimental toothpaste with stannous fluoride to see if it could improve gum health and reduce plaque better than regular fluoride toothpaste. 154 adults with mild gum disease (gingivitis) brushed with either the test or regular toothpaste for 12 weeks. Rese…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Laser zaps brace pain and speeds up teeth straightening
Symptom relief CompletedThis study tested whether low-level laser therapy (LLLT) can reduce pain, speed up tooth movement, and improve gum health in people getting braces. 108 Pakistani adults aged 18-30 with mild crowding received either LLLT or no laser during their first six months of treatment. The …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Aga Khan University • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Mouthwash showdown: new formula takes on standard rinse for healthier gums
Symptom relief CompletedThis study tested whether a new mouthwash (MicroRepair® ABX) works as well as a standard antiseptic rinse (chlorhexidine) for treating gum inflammation caused by plaque. Forty adults with gingivitis received professional teeth cleaning, then used one of the two mouthwashes twice …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Pavia • Aim: Symptom relief
Last updated May 11, 2026 20:53 UTC
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Probiotic shows promise for Braces-Related gum troubles
Symptom relief CompletedThis study tested whether taking a specific probiotic (Limosilactobacillus reuteri) can improve gum health in adults with braces who also have gingivitis (gum inflammation). 100 participants were randomly assigned to receive the probiotic or no treatment. The main goal was to mea…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Medical University of Warsaw • Aim: Symptom relief
Last updated May 11, 2026 20:51 UTC
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New toothpaste and mouthwash combo takes on gingivitis
Symptom relief CompletedThis study tested whether a special dental routine (PerioGard toothpaste, mouthwash, and toothbrush) works better than standard products at reducing plaque and gum inflammation (gingivitis). Eighty adults with mild to moderate gum disease used the products at home for three month…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 11, 2026 20:39 UTC
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Braces and bleeding gums? new study tests smarter cleaning
Symptom relief CompletedThis study tested two professional dental cleaning methods in 30 adults with braces and gum inflammation (gingivitis). Each participant received both a newer guided biofilm therapy and a conventional cleaning on different sides of their mouth. Researchers measured plaque removal,…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: King Abdullah University Hospital • Aim: Symptom relief
Last updated Apr 26, 2026 19:37 UTC
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Which whitening tray works best? study compares patient satisfaction
Symptom relief CompletedThis study compared two types of custom-made trays used for at-home teeth whitening. Forty adults used either an Essix-type retainer or a Vivera retainer with the same whitening gel for four weeks. Researchers measured how satisfied patients were with each tray, how well they whi…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated Apr 20, 2026 16:14 UTC
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Gum health may reveal hidden inflammation in diabetic kidney disease
Knowledge-focused CompletedThis study looked at 126 people with type 2 diabetes, some with kidney complications, to measure inflammation markers in their saliva and blood. Researchers compared these markers based on gum health status. The goal was to better understand the links between gum disease, diabete…
Matched conditions: GINGIVITIS
Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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Saliva test could spot gum disease early
Knowledge-focused CompletedThis study looked at whether certain proteins in saliva (IL-6, IL-8, and LIGHT) can help tell the difference between healthy gums, gingivitis, and periodontitis. Researchers measured these proteins in 60 non-smoking adults with no other health conditions. The goal was to see if t…
Matched conditions: GINGIVITIS
Sponsor: Izmir Katip Celebi University • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Gum disease disrupts body's internal clock, study finds
Knowledge-focused CompletedThis study looked at whether gum disease (gingivitis or periodontitis) changes how the body's natural clock works in gum tissue. Researchers studied 60 healthy adults with similar sleep patterns. They collected small gum tissue samples and measured clock-related genes and protein…
Matched conditions: GINGIVITIS
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated May 07, 2026 18:42 UTC
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Gum disease study tracks mouth's inflammation signals before and after cleaning
Knowledge-focused CompletedThis study looked at two substances in the fluid around teeth—fractalkine and CX3CR1—that are linked to inflammation. Researchers measured them in 90 adults with healthy gums, gingivitis, or periodontitis before and after a deep cleaning. The goal was to see how these markers cha…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Giresun University • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC
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Gum Therapy's hidden impact on jaw bone revealed
Knowledge-focused CompletedThis study examined how standard non-surgical gum disease treatment changes the bone supporting your teeth. Researchers analyzed dental X-rays from 69 people with gum disease or gingivitis, taken before and 6 months after treatment. They used a special computer method called frac…
Matched conditions: GINGIVITIS
Sponsor: Akdeniz University • Aim: Knowledge-focused
Last updated May 05, 2026 11:56 UTC