GINGIVITIS
Clinical trials for GINGIVITIS explained in plain language.
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New mouthwash fights plaque to protect dental implants
Disease control CompletedThis study tested whether a new mouthwash containing CPC, hyaluronic acid, and zinc lactate works better than a standard fluoride mouthwash at reducing plaque and preventing gum inflammation around dental implants. It involved 80 adults with dental implants who used the assigned …
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Special gum tested to fight gum disease and boost heart health
Disease control CompletedThis study tested whether a chewing gum containing dietary nitrate (a compound found in vegetables like beets) could improve gum health and heart health. For three weeks, adults with mild to moderate gum irritation chewed either the special gum or a placebo gum. Researchers measu…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New mouthwash formula tested to fight gum disease
Disease control CompletedThis study compared two different mouthwash formulas to see which one works better at reducing gum inflammation and preventing gum disease from coming back. 72 people with gingivitis used either a standard 0.12% chlorhexidine mouthwash or a new formula with a lower dose of chlorh…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Siena • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New dental duo fights gum disease?
Disease control CompletedThis study tested if using a specific stannous fluoride toothpaste together with a cetylpyridinium chloride mouthwash twice daily improves gum health and reduces plaque better than using a regular fluoride toothpaste alone. It involved 199 adults with mild to moderate gum inflamm…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Ancient seed in toothpaste fights soldier gum disease
Disease control CompletedThis study tested whether a toothpaste containing Nigella sativa (black seed) could help control gum inflammation. Researchers measured specific markers of inflammation in the saliva of 100 Indonesian Army soldiers with gingivitis before and after using the toothpaste. The goal w…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Universitas Airlangga • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Herbal mouthwash challenge: can it beat the standard without the stains?
Disease control CompletedThis study tested whether a new herbal mouthwash and gel (StellaLife) could control plaque and gum inflammation as effectively as the standard chlorhexidine rinse, which can stain teeth and alter taste. Thirty-four healthy volunteers used each product for two weeks without brushi…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Stony Brook University • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Floss vs. mouthwash: which is better for your gums?
Disease control CompletedThis study aimed to find out which works better for reducing plaque and gum inflammation: dental floss or different types of mouthwash. It involved 228 adults with existing gum inflammation. Researchers compared floss against three mouthwashes to see which was most effective at c…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New toothpaste formula tested to fight gum disease
Disease control CompletedThis study tested whether a new Colgate toothpaste with dual zinc ingredients works better than their standard cavity protection toothpaste at reducing plaque and gum inflammation (gingivitis). 86 adults with existing plaque and mild gum inflammation used one of the two toothpast…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New toothbrush design aims to fight gum disease
Disease control CompletedThis study tested whether a new type of electric toothbrush that cleans the whole mouth at once is better at reducing gum inflammation and plaque than a standard electric toothbrush. 94 adults with mild to moderate gum inflammation used one of the assigned brushes for 30 days. Re…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: University of Minnesota • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New toothpaste formula aims to fight gum bleeding
Disease control CompletedThis study tested whether a new experimental toothpaste containing stannous fluoride could improve gum health and reduce plaque better than a regular fluoride toothpaste. About 154 adults with mild gum inflammation used one of the toothpastes twice daily for 12 weeks. Researchers…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Special toothpaste & mouthwash combo tested for better gum health
Disease control CompletedThis 12-week study tested if using a specific toothpaste and mouthwash together works better than regular toothpaste alone to reduce plaque and help with gum problems. It involved 90 adults with existing plaque and mild gum inflammation. Researchers measured changes in plaque bui…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Special toothpaste & mouthwash combo tested to fight gum disease
Disease control CompletedThis study tested whether a specific toothpaste and mouthwash combination works better than a regular fluoride toothpaste to reduce plaque buildup and gum inflammation (gingivitis). 82 adults with existing plaque and gingivitis used their assigned products at home for 12 weeks an…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Can switching from cigarettes to vapes give you a healthier smile?
Disease control CompletedThis study looked at whether smokers who switch to e-cigarettes or heated tobacco products see improvements in their gum health and teeth appearance. It followed 460 adult smokers and non-smokers for 18 months, comparing those who kept smoking, those who switched to smoke-free al…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Eclat Srl. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Can a battery toothbrush beat gum disease? new study investigates
Disease control CompletedThis study tested whether using a specific battery-powered toothbrush and toothpaste is better at reducing plaque and gum inflammation (gingivitis) than regular brushing. It involved 130 adults with mild gum disease who used the assigned products for 12 weeks. Dentists measured p…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New dental duo battles plaque and gum disease in 3-Month test
Disease control CompletedThis study tested whether a new stannous fluoride toothpaste and specially designed toothbrush work better than standard products at reducing plaque buildup and gum inflammation (gingivitis). 95 adults in Thailand with existing plaque and mild gum inflammation used their assigned…
Matched conditions: GINGIVITIS
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Can your toothbrush fight gum disease? 6-Week study investigates
Disease control CompletedThis study tested how well different manual toothbrushes reduce plaque buildup and mild gum inflammation (gingivitis). 84 adults with existing plaque and gingivitis used the assigned toothbrush at home for 6 weeks. Researchers checked their plaque and gum health at 1, 3, and 6 we…
Matched conditions: GINGIVITIS
Phase: PHASE2 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New mouthwash tested to fight gum disease
Disease control CompletedThis 12-week study tested if adding an experimental mouthwash containing cetylpyridinium chloride (CPC) to regular brushing with fluoride toothpaste could improve gum health and reduce plaque better than brushing alone. It involved 136 adults with mild to moderate gingivitis. Res…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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New gum care routine put to the test
Disease control CompletedThis study tested whether a specific oral care routine could better control gum inflammation (gingivitis) compared to regular brushing. For six weeks, one group used a powered toothbrush followed by a mouthwash twice daily, while another group brushed normally with a manual tooth…
Matched conditions: GINGIVITIS
Phase: PHASE4 • Sponsor: Procter and Gamble • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New toothpaste formula tested to fight gum bleeding and plaque
Disease control CompletedThis 4-week study tested whether a new experimental toothpaste could improve gum health better than a regular fluoride toothpaste. It involved 175 adults with mild to moderate gum inflammation. Researchers compared how well each toothpaste reduced gum bleeding and plaque buildup …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New vs. old: which dental cleaning works best for braces wearers?
Disease control CompletedThis study compared two professional dental cleaning methods for people with braces who have gum inflammation (gingivitis). Thirty participants received both a newer 'Guided Biofilm Therapy' and a traditional cleaning, one on each side of their mouth, to see which was better at r…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: King Abdullah University Hospital • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Ancient herbal remedy takes on gold standard mouthwash in gum disease fight
Disease control CompletedThis study tested whether a traditional herbal mouthwash called Triphala works as well as the standard chlorhexidine mouthwash for controlling plaque and gum inflammation (gingivitis). Researchers compared the two mouthwashes in 220 adults with mild to moderate gingivitis. The go…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Bangladesh Medical University • Aim: Disease control
Last updated Mar 11, 2026 14:52 UTC
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Could a painless laser make braces faster and more comfortable?
Symptom relief CompletedThis study tested if a gentle, painless laser treatment could help people wearing braces. Researchers wanted to see if the laser could reduce common problems like pain and gum inflammation, and possibly help teeth move faster. They compared two groups of 108 young adults getting …
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Aga Khan University • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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Which whitening tray works best? study reveals patient preferences
Symptom relief CompletedThis study compared two common types of clear plastic trays used for at-home teeth whitening. Researchers wanted to see which tray patients preferred and which caused less tooth sensitivity or gum irritation. Forty adults used a whitening gel in either an Essix-type tray or a Viv…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated Mar 19, 2026 14:55 UTC
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Spit test could reveal hidden health links
Knowledge-focused CompletedThis study aimed to better understand the links between gum disease, type 2 diabetes, and diabetic kidney disease by measuring specific inflammation markers. Researchers compared 126 people with either newly diagnosed diabetes or diabetes with kidney problems, grouping them by th…
Matched conditions: GINGIVITIS
Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists search for gum disease clues in your Mouth's fluid
Knowledge-focused CompletedThis study aimed to understand gum disease better by measuring specific inflammation markers in the fluid around the gums. It involved 90 people with healthy gums, gingivitis, or periodontitis. Researchers collected fluid samples before and after a standard professional teeth cle…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: Giresun University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists probe baking Soda's secret effect on gum disease bugs
Knowledge-focused CompletedThis study aimed to understand how a toothpaste containing baking soda affects the community of bacteria in the mouth over 12 weeks. It compared this toothpaste to a regular fluoride toothpaste in 74 adults with mild to moderate gum inflammation. The main goal was to see if the b…
Matched conditions: GINGIVITIS
Phase: NA • Sponsor: HALEON • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Spit test for gum disease? researchers hunt for clues in saliva
Knowledge-focused CompletedThis study aimed to find out if certain inflammation markers in saliva can be used to diagnose gum disease. Researchers collected saliva from 60 people with healthy gums, gingivitis, or periodontitis. They measured three specific proteins to see if their levels differed between t…
Matched conditions: GINGIVITIS
Sponsor: Izmir Katip Celebi University • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:03 UTC
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Scientists probe if gum disease throws off your Body's clock
Knowledge-focused CompletedThis study aimed to understand if gum inflammation is linked to changes in the body's internal clock within the gums themselves. Researchers compared 60 adults with similar sleep patterns, who had either healthy gums, gingivitis, or more serious periodontitis. They analyzed small…
Matched conditions: GINGIVITIS
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC