Baking soda toothpaste may alter gum bacteria, small study suggests
NCT ID NCT07273539
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how a toothpaste with sodium bicarbonate (baking soda) affects the bacteria living in the mouth over 12 weeks. Seventy-four adults with mild gum inflammation (gingivitis) used either the baking soda toothpaste or a regular fluoride toothpaste. Researchers checked changes in the types and activity of bacteria in dental plaque. The goal was to understand if baking soda toothpaste can positively influence the oral microbiome.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sodium bicarbonate toothpaste
What this could lead to
If successful, this could show that baking soda toothpaste helps maintain a healthier balance of mouth bacteria, potentially improving gum health.
What could go wrong
This is a small, early-stage study focused on microbiome changes, not on curing gum disease. Results may not translate to better clinical outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Birmingham
Birmingham, B5 7EG, United Kingdom