Gum fluid proteins may reveal hidden clues about periodontitis
NCT ID NCT06727929
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study measured two proteins, Dkk-1 and sFRP5, in the gum fluid of 99 people with healthy gums, gingivitis, or periodontitis. Researchers collected samples before and after non-surgical periodontal treatment (deep cleaning) to see if these proteins change with treatment. The goal was to explore whether these proteins could serve as markers for gum disease activity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
non-surgical periodontal treatment (scaling and root planing)
What this could lead to
If successful, this could point toward a new way to diagnose or monitor gum disease using protein levels in gum fluid.
What could go wrong
This is a small, completed study that only measured protein levels; it does not test a new treatment. The results may not apply to broader populations or lead to a diagnostic test.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sivas Cumhuriyet University
Sivas, Turkey (Türkiye)